Browsing INVESTIGACIÓN by Author "Ibáñez Solé, Olga"
Now showing items 1-4 of 4
-
Age or lifestyle-induced accumulation of genotoxicity is associated with a length-dependent decrease in gene expression
DNA damage has long been advocated as a molecular driver of aging. DNA damage occurs in a stochastic manner, and is therefore more likely to accumulate in longer genes. The length-dependent accumulation of transcription-blocking ... -
Amplicon metagenomics for elucidating microbial community changes associated to conventional and organic farming of Beta vulgaris and Solanum lycopersicum
Ibáñez Solé, Olga (2016-04-27)Soil microbial community changes associated to conventional and organic farming of two relevant crops (Beta vulgaris and Solanum lycopersicum) were analysed through 16s rRNA amplicon sequencing. This study revealed microbial ... -
Exploring the transcriptional hallmarks of aging using single-cell RNA sequencing
Ibáñez Solé, Olga (2023-11-14)Aging is associated with a series of phenotypic changes at the cellular level, including changes in gene expression. In recent years, aged tissues have been reported to present an increase in transcriptional noise or ... -
Triku: a feature selection method based on nearest neighbors for single-cell data
Ascensión, Alex M.; Ibáñez Solé, Olga; Inza Cano, Iñaki ; Izeta Permisán, Ander ; Araúzo Bravo, Marcos J. (Oxford University Press, 2022-03-12)Abstract BACKGROUND: Feature selection is a relevant step in the analysis of single-cell RNA sequencing datasets. Most of the current feature selection methods are based on general univariate descriptors of the data ...