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Now showing items 3341-3350 of 3386
Human ATG3 binding to lipid bilayers: role of lipid geometry, and electric charge
(Nature Publishing, 2017-11-15)
Specific protein-lipid interactions lead to a gradual recruitment of AuTophaGy-related (ATG) proteins to the nascent membrane during autophagosome (AP) formation. ATG3, a key protein in the movement of LC3 towards the ...
Triacylglycerol mimetics regulate membrane interactions of glycogen branching enzyme: implications for therapy
(Elsevier, 2017-06-19)
Adult polyglucosan body disease (APBD) is a neurological disorder characterized by adult-onset neurogenic bladder, spasticity, weakness, and sensory loss. The disease is caused by aberrant glycogen branching enzyme (GBE) ...
Small Form-Factor Driver for Power LEDs Powered with One Element Battery
(Springer, 2011)
The present paper is focused on designing small form-factor drivers for high-power LEDs, which are fed with one battery element. Standard power supply architectures are not suitable due to the design requirements and ...
Multiple-Criteria Decision-Making Tool for Local Governments to Evaluate the Global and Local Sustainability of Transportation Systems in Urban Areas: Case Study
(ASCE, 2017-10-24)
Efficient management of urban transportation systems is a challenge for any local government that wishes to improve public wellbeing and comfort. With that end in mind, this paper proposes a tool for decision making and ...
Speed deficiency in shipbuilding contracts from the point of view of an efficient managing of the main engine
(University of Santander, 2010)
This article is related to the shipbuilding contracts and its purpose is to provide amethod of calculation of the economical damages sustained by a purchaser due tothe speed deficiency of the vessel delivered by the shipyard. ...
Combined Fluorescent-Chromogenic In Situ Hybridization for Identification and Laser Microdissection of Interphase Chromosomes
(Public Library of Science, 2013)
Chromosome territories constitute the most conspicuous feature of nuclear architecture, and they exhibit non-random distribution patterns in the interphase nucleus. We observed that in cell nuclei from humans with Down ...
Stability of CuZnOAl2O3/HZSM-5 and CuFe2O4/HZSM-5 catalysts in dimethyl ether steam reforming operating in reaction-regeneration cycles
(Elsevier, 2014-05-21)
The study focuses on the regenerability of bifunctional catalysts prepared with different metallic functions (CuZnOAl2O3 and CuFe2O4 spinel) and HZSM-5 zeolite (SiO2/Al2O3 = 30) as the acid function. These catalysts have ...
Steam reforming of raw bio-oil in a fluidized bed reactor with prior separation of pyrolytic lignin
(ACS, 2013-11-11)
The effect operating conditions (temperature, steam/carbon molar ratio and space-velocity) have on the steam reforming of raw bio-oil has been studied in a two-step reaction unit. In the first step (operated at 500 ºC), a ...
A systematic review and meta-analysis of MTHFR polymorphisms in methotrexate toxicity prediction in pediatric acute lymphoblastic leukemia
(Springer, 2013-10-23)
Methotrexate (MTX) is an important component of therapy used to treat childhood acute lymphoblastic leukemia (ALL). Two single-nucleotide polymorphisms (SNPs) in the methylenetetrahydrofolate reductase (MTHFR) gene, C677T ...
MTHFR Polymorphisms In Childhood Acute lymphoblastic Leukemia: Influence On Methotrexate Therapy
(Dove Medical Press LTD, 2017)
Methotrexate (MTX) is an important component in the therapy used to treat childhood
acute lymphoblastic leukemia (ALL). Methylenetetrahydrofolate reductase (MTHFR) is a key
enzyme for MTX pharmacokinetics. Two single-nucleotide ...