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Now showing items 11-20 of 21
An Overview on the Field of Micro- and Nanotechnologies for Synthetic Peptide-Based Vaccines
(Hindawi Publishing Corporation, 2011)
The development of synthetic peptide-based vaccines has many advantages in comparison with vaccines based on live attenuated organisms, inactivated or killed organism, or toxins. Peptide-based vaccines cannot revert to a ...
Increased antiparkinson efficacy of the combined administration of VEGF- and GDNF-loaded nanospheres in a partial lesion model of Parkinson's disease
(Dove Medical Press, 2014)
Current research efforts are focused on the application of growth factors, such as glial cell line-derived neurotrophic factor (GDNF) and vascular endothelial growth factor (VEGF), as neuroregenerative approaches that will ...
Zelula mikrokapsularatu bioaktiboak sendagaien askapen egonkorrerako
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2012)
Zelula bioaktiboen mikrokapsularatzea delako teknologia hainbat terapiatan erabiltzen da. Sistema honen bidez, era seguru batean ezartzen dira terapia-produktu batzuk askatzen dituzten zelulak; horrela, epe luzerako ehun ...
Preparation and Characterization of Resveratrol Loaded Pectin/Alginate Blend Gastro-Resistant Microparticles
(MDPI, 2018-08)
Background: The use of resveratrol as a dietary supplement is limited because it is easily oxidized and, after oral ingestion, it is metabolized into enterocytes and hepatocytes. Thus, new formulations are needed in order ...
rhegf-Loaded Plga-Alginate Microspheres Enhance The Healing Of Full-Thickness Excisional Wounds In Diabetised Wistar Rats
(Elsevier, 2013)
[EN] Diabetic foot ulcers (DFUs) represent a major clinical challenge in the ageing
population. To address this problem, rhEGF-loaded Poly-Lactic-co-Glycolic-Acid (PLGA)-Alginate microspheres (MS) were prepared by a ...
Behavior And Ultrastructure Of Human Bone Marrow-Derived Mesenchymal Stem Cells Immobilized In Alginate-Poly-L-Lysine-Alginate Microcapsules
(Taylor & Francis, 2014-04-24)
Context: Human bone marrow mesenchymal stem cells (hBM-MSCs) show a great promise for the treatment of a variety of diseases. Despite the previous trials to encapsulate hBM-MSCs in alginate-poly-l-lysine-alginate (APA) ...
Improvement of the monitoring and biosafety of encapsulated cells using the SFGNESTGL triple reporter system
(Elsevier, 2010-05-23)
Cell microencapsulation may represent a breakthrough to overcome problems associated with cell therapy. Advances in material biocompatibility and production protocols have put this field close to its clinical application. ...
Inactivation of encapsulated cells and their therapeutic effects by means of TGL triple-fusion reporter/biosafety gene
(Elsevier, 2012-11-19)
The immobilization of cells within alginate-poly-l-lysine-alginate (APA) microcapsules has been demonstrated to be an effective technology design for long term delivery of therapeutic products. Despite promising advances, ...
Novel advances in the design of three-dimensional bio-scaffolds to control cell fate: translation from 2D to 3D
(Elsevier, 2012-05-07)
Recreating the most critical aspects of the native extracellular matrix (ECM) is fundamental to understand and control the processes regulating cell fate and cell function. From the ill-defined complexity to the controlled ...
Optimization of 100 µm alginate-poly-L-lysine-alginate capsules for intravitreous administration
(Elsevier, 2011-09-24)
The field of cell microencapsulation is advancing rapidly. Particle size plays a critical role in terms of biocompatibility and limits decisively its applicability. Producing reduced size microcapsules involves broadening ...