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Now showing items 7471-7480 of 7550
SNPs in microRNAs and susceptibility to Late-Onset Alzheimer´s disease
(2014-06-24)
Case-control association study of SNPs in microRNAs and susceptibility to Late-Onset Alzheimer´s disease.
miRNA polymorphisms are associated with risk of developing chronic lymphocytic leukemia
(2015-04-01)
Chronic Lymphocytic Leukemia (CLL) is the most frequent leukemia of adults in
Western countries and shows a ~8.5-fold increased relative risk in first-degree relatives.
Up to date several studies have identified ...
Genetic Variants in MiRNA Processing Genes and Pre-MiRNAs Are Associated with the Risk of Chronic Lymphocytic Leukemia
(Public Library Science, 2015-03-20)
Genome wide association studies (GWAS) have identified several low-penetrance susceptibility alleles in chronic lymphocytic leukemia (CLL). Nevertheless, these studies scarcely study regions that are implicated in non-coding ...
MTHFR polymorphisms in childhood acute lymphoblastic leukemia: influence on methotrexate therapy
(Dove Medical Press, 2017-03-27)
Methotrexate (MTX) is an important component in the therapy used to treat childhood acute lymphoblastic leukemia ( ALL). Methylenetetrahydrofolate reductase ( MTHFR) is a key enzyme for MTX pharmacokinetics. Two single-nucleotide ...
Pharmacogenetics of MicroRNAs and MicroRNAs Biogenesis Machinery in Pediatric Acute Lymphoblastic Leukemia
(Public Library Science, 2014-03-10)
Despite the clinical success of acute lymphoblastic leukemia (ALL) therapy, toxicity is frequent. Therefore, it would be useful to identify predictors of adverse effects. In the last years, several studies have investigated ...
Teachers’ knowledge of ADHD: relevance of training and individual perceptions
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2016)
El presente estudio analiza el conocimiento que los maestros presentan sobre el TDAH y su relación con diversas variables formativas y auto-perceptivas. La muestra estuvo compuesta por 1278 docentes de 108 centros escolares. ...
The Emotional Divergent–Convergent Thinking Program (EDICOP): Design, Implementation, and Results
(MDPI, 2020-11-13)
In a social environment that requires young people to adapt to increasingly demanding situations, emotional education and creativity training may be key for both personal development and academic performance. Given that ...
Age‐related cognitive decline in myotonic dystrophy type 1: An 11‐year longitudinal follow‐up study
(Wiley, 2020-03)
Background Myotonic dystrophy type 1 (DM1) is an inherited multi-systemic disease involving the central nervous system (CNS) and is consequently characterized by a range of cognitive impairments. However, whether this ...
Lipid regulation of Atg8 family protein recruitment and membrane modulation of mitophagy and autophagic cell death
(2017-01-20)
Tesi lan honen aurkikuntzek, mitofagian zehar LC3/GABARAP familiako proteinen mitokondrioetarako errekrutatze-prozesuaren mekanismo molekularraren eta Atg8 proteinaren giza ortologoek giza lerro zelular ezberdinetan daukaten ...
Genetic variants involved in Childhood Acute Lymphoblastic Leukemia Susceptibility
(2016-12-15)
La Leucemia linfoblástica aguda (LLA) infantil es el cáncer pediátrico más común. El hecho de que se desarrolle a una edad temprana sugiere que para su aparición debe existir un fuerte componente genético. Recientes GWAS ...