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Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action
(Elsevier, 2020-06-12)
[EN] Bipolar disorder (BD) is a major healthcare and socio-economic challenge. Despite its substan- tial burden on society, the research activity in BD is much smaller than its economic impact appears to demand. There is ...
Design and Manufacture of Bone Cements Based on Calcium Sulfate Hemihydrate and Mg, Sr-Doped Bioactive Glass
(MDPI, 2023-10-18)
In the present study, a novel composite bone cement based on calcium sulfate hemihydrate (CSH) and Mg, Sr-containing bioactive glass (BG) as solid phase, and solution of chitosan as liquid phase were developed. The phase ...
Lenvatinib-Loaded Poly(lactic-co-glycolic acid) Nanoparticles with Epidermal Growth Factor Receptor Antibody Conjugation as a Preclinical Approach to Therapeutically Improve Thyroid Cancer with Aggressive Behavior
(MDPI, 2023-11-13)
Background: Lenvatinib, a tyrosine kinase inhibitor (TKI) approved for the treatment of progressive and radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC), is associated with significant adverse effects ...
Rhabdomyosarcoma: Current Therapy, Challenges, and Future Approaches to Treatment Strategies
(MDPI, 2023-11-02)
Rhabdomyosarcoma is a rare cancer arising in skeletal muscle that typically impacts children and young adults. It is a worldwide challenge in child health as treatment outcomes for metastatic and recurrent disease still ...
Application of a Platform for Gluten-Free Diet Evaluation and Dietary Advice: From Theory to Practice
(MDPI, 2022-01-19)
The present work aimed to analyze, through the GlutenFreeDiet digital platform, the evolution over one year of the nutritional status, dietary profile and symptoms present among celiac people on a gluten-free diet (GFD) ...
Nutritional Imbalances in Adult Celiac Patients Following a Gluten-Free Diet
(MDPI, 2021-08-21)
Celiac disease (CD) is a chronic autoimmune disorder of the small intestine, whose only effective treatment is a gluten-free diet (GFD). It is characterized by the atrophy of the intestinal villi that leads to altered ...
Health financing policies during the COVID-19 pandemic and implications for universal health care: a case study of 15 countries
(Elsevier, 2023-12)
Background The COVID-19 pandemic was a health emergency requiring rapid scal resource mobilisation to support national responses. The use of e ective health nancing mechanisms and policies, or lack thereof, a ected the ...
Pharmaceutical residues in stranded dolphins in the Bay of Biscay
(Elsevier, 2023-11-17)
There is a growing concern about the presence of pharmaceuticals on all trophic levels of the 3 aquatic environment. The presence of pharmaceuticals in the marine environment, which is the 4 final receiver of the continental ...
Population Pharmacokinetics of Levetiracetam and Dosing Evaluation in Critically Ill Patients with Normal or Augmented Renal Function
(MDPI, 2021-10-15)
Levetiracetam is a broad-spectrum antiepileptic drug commonly used in intensive care units (ICUs). The objective of this study is to evaluate the adequacy of levetiracetam dosing in patients with normal or augmented renal ...
Suckling or non-suckling? Sensory characterization of commercialized lamb meat according to feeding
(Wiley, 2023-08-25)
Consumption of meat from suckling lambs is typical in some regions. However, sensory
differences between meat from suckling and non-suckling
lambs are barely described
in previous studies. The objectives of the present ...