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Germline Gene Editing: The Gender Issues
(Cambridge University Press, 2023-04)
Human germline gene editing constitutes an extremely promising technology; at the same time, however, it raises remarkable ethical, legal, and social issues. Although many of these issues have been largely explored by the ...
Intelligent Sitting Posture Classifier for Wheelchair Users
(IEEE, 2023)
In recent years, there has been growing interest in postural monitoring while seated, thus preventing the appearance of ulcers and musculoskeletal problems in the long term. To date, postural control has been carried out ...
Redox regulation of KV7 channels through EF3 hand of calmodulin
(eLife Sciences, 2023-01)
Neuronal KV7 channels, important regulators of cell excitability, are among the most sensitive proteins to reactive oxygen species. The S2S3 linker of the voltage sensor was reported as a site-mediating redox modulation ...
The role of E2F1 and E2F2 in liver disease.
(2023-03-24)
El estilo de vida occidental ha provocado un aumento de la prevalencia de varias enfermedades que afectan al hígado. Por un lado, la obesidad, que se ha convertido en una pandemia mundial, aumenta el riesgo de desarrollar ...
Eficacia del Plasma Rico en Plaquetas: Influencia de la vía de administración y edad del donante.
(2023-05-19)
La artrosis de rodilla es una enfermedad prevalente de difícil control. Las terapias con PRP para el tratamiento de esta patología han demostrado un buen control clínico de la enfermedad. Diversos factores influyen en los ...
Plasma rico en plaquetas en la artrosis severa de cadera: acción biológica y perspectivas terapéuticas.
(2023-05-19)
La artrosis de cadera es una enfermedad inflamatoria de bajo grado, altamente prevalente en la población mundial. Los tratamientos conservadores de esta enfermedad se limitaban al tratamiento de los síntomas asociados. La ...
The Role of Sperm Membrane Potential and Ion Channels in Regulating Sperm Function
(MDPI, 2023-04-10)
During the last seventy years, studies on mammalian sperm cells have demonstrated the essential role of capacitation, hyperactivation and the acrosome reaction in the acquisition of fertilization ability. These studies ...
Mortality Risks after Two Years in Frail and Pre-Frail Older Adults Admitted to Hospital
(MDPI, 2023-04-24)
Background: Frailty is characterized by a progressive decline in the physiological functions of multiple body systems that lead to a more vulnerable condition, which is prone to the development of various adverse events, ...
Notch and Wnt Signaling Modulation to Enhance DPSC Stemness and Therapeutic Potential
(MDPI, 2023-04-17)
The Dental Pulp of permanent human teeth is home to stem cells with remarkable multilineage differentiation ability: human Dental Pulp Stem Cells (DPSCs). These cells display a very notorious expression of pluripotency ...
The role of scavenger receptor MARCO in the immuno-oncology of intrahepatic cholangiocarcinoma: a novel prognostic and therapeutic target
(2023-03-03)
El colangiocarcinoma (CCA) es un conjunto de tumores que se originan en la vía biliar y debido a su carácter asintomático, se diagnostican en fases muy avanzadas, limitando sustancialmente las posibles opciones terapéuticas. ...