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Oncostatin M Signalling in Cancer-Related Inflammation: Implications in Breast Cancer and Hepatocellular Carcinoma
(2023-05-19)
El cáncer y la inflamación están estrechamente relacionadas de forma bidireccional, y la inflamación crónica está considerada como una característica intrínseca del cáncer. La Oncostatina M (OSM) es una citoquina inflamatoria ...
Importancia de las peptidasas como indicadores de la calidad seminal y embrionaria humana.
(2023-07-18)
Las terapias de reproducción asistida (TRA) son esenciales para el tratamiento de una cantidad creciente parejas con problemas reproductivos. La mejora de estas técnicas pasa, entre otros aspectos, por el hallazgo de ...
Sensorized Tip for Monitoring People with Multiple Sclerosis that Require Assistive Devices for Walking
(MDPI, 2020-08-03)
Multiple Sclerosis (MS) is a neurological degenerative disease with high impact on our society. In order to mitigate its effects, proper rehabilitation therapy is mandatory, in which individualisation is a key factor. ...
Factores asociados al dolor lumbar y estado psicoafectivo de las auxiliares de geriatría en residencias de mayores
(Euskal Herriko Ubibertsitatea/Universidad del País Vasco, 2020-06)
INTRODUCCIÓN:
Diferentes estudios observan que la sobrecarga a nivel físico y psicoafectivo de las auxiliares de geriatría (AG) que trabajan en residencias de mayores es muy elevada. Dado que esta sobrecarga puede tener ...
The Nutritional Status of Long-Term Institutionalized Older Adults Is Associated with Functional Status, Physical Performance and Activity, and Frailty
(MDPI, 2021-10-22)
Among older adults living in long-term nursing homes (LTNHs), maintaining an adequate functional status and independence is a challenge. Whilst a poor nutritional status is a potential risk factor for a decreased function ...
Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells
(MDPI, 2020-03-07)
Dental pulp stem cells (DPSCs) from adult teeth show the expression of a very complete repertoire of stem pluripotency core factors and a high plasticity for cell reprogramming. Canonical Wnt and Notch signaling pathways ...
A preliminary analysis of gait performance of patients with multiple sclerosis using a sensorized crutch tip
(Elsevier, 2020-07-17)
The quality of life and functional mobility of patients with Multiple Sclerosis (MS) can significantly improve with exercise and a rehabilitation therapy adjusted to the needs of each patient. The assessment of gait and ...
An Epilepsy-Causing Mutation Leads to Co-Translational Misfolding of the Kv7.2 Channel
(Springer, 2021-05-21)
BACKGROUND: The amino acid sequence of proteins generally carries all the necessary information for acquisition of native conformations, but the vectorial nature of translation can additionally determine the folding outcome. ...
The Multifunctional Role of SPANX-A/D Protein Subfamily in the Promotion of Pro-Tumoural Processes in Human Melanoma
(Nature, 2021-02-11)
Human sperm protein associated with the nucleus on the X chromosome (SPANX) genes encode a protein family (SPANX-A, -B, -C and -D), whose expression is limited to the testis and spermatozoa in normal tissues and various ...
(Pro)renin Receptor Is Present in Human Sperm and It Adversely Affects Sperm Fertility Ability
(MDPI, 2021-03-22)
Sperm fertility ability may be modulated by different molecular systems, such as the renin-angiotensin system (RAS). Although renin is one of its most relevant peptides, the presence and role of the (pro)renin receptor ...