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Chemoenzymatic synthesis and immunological studies of Xylosylated N-glycans
(2016-06-07)
Glycosylation is one of the most common post-translational modifications in eukaryotic cells. It changes during cell development and differentiation and it is tissue and more importantly, species specific. While core ¿-1,6 ...
Synthèse et caractérisation de particules thermosensibles de poly(N-vinylcaprolactame) par polymérisation en émulsion en utilisant un stabilisant macromoléculaire réactif
(2016-12-16)
Résumé : Au cours de cette thèse, deux types de particules thermosensibles de poly(N-vinylcaprolactame) (PVCL) ont été synthétisées par polymérisation en émulsion en utilisant un stabilisant macromoléculaire porteur d'une ...
Osteopontin: a key regulator of liver lipid metabolism
(2016-04-25)
Osteopontin deficiency protects from obesity-related hepatosteatosis and liver fibrosis. Here we have investigated the role of osteopontin as a direct regulator of liver metabolism and whether osteopontin could be a ...
RESTful framework for collaborative internet of things based on IEC 61850
(2016-02-08)
En 1991, Mark Weiser formuló el paradigma de Computación Ubicua definiendo el concepto de Entorno Inteligente como un espacio físico repleto de dispositivos, muy integrados en el entorno, y con capacidades de identificación, ...
Investigation of Mg-Zn-Al metal alloys as new PCMs for latent heat energy storage applications
(2016-12-19)
The main objective of this thesis is to investigate metal alloys as phase change material (PCM) for thermal energy storage (TES) applications. In particular, This work consists to analyze and characterize a set of binary ...
Development of protective coatings to improve the Ti6Al4V alloy behavior in orthopedic applications
(2016-01-15)
Hoy en día, debido al aumento de la esperanza de vida, al elevado ritmo de vida y al aumento del número de personas que practican deporte, es necesario que el ser humano esté activo y dinámico durante más tiempo. Esto ...
Enhancing sampling in computational statistics using modified hamiltonians
(2016-11-18)
The Hamiltonian Monte Carlo (HMC) method has been recognized as a powerful sampling tool in computational statistics. In this thesis,we showthat performance ofHMCcan be dramatically improved by replacing Hamiltonians in ...
The role of seas as a geographical barrier for migratory landbirds. An approach to the Bay of Biscay.
(2016-11-24)
The East-Atlantic flyway represents one of the main bird migration routes worldwide, comprising the Bay of Biscayas an inherent geographical barrier. So far, the significance of the Bay of Biscay for migrants and its ...
Elementary reactive processes of nitrogen and hydrogen on metal surfaces: A theoretical study
(2016-12-16)
We present a theoretical study of elementary reaction take place at solid surfaces. Calculations based on density functional theory (DFT) were performed to obtain the minimum energy structure of the Fe(111) surface as well ...
Post-translational modifications by sumo and ubiquitin-like proteins; role of sumoylation on sall proteins
(2016-02-18)
Las modificaciones post-traduccional debidas a la conjugación de Ubiquitina y de proteínas similares a la Ubiquitina (UbLs) contribuyen a extender y diversificar la funcionalidad de los proteomas eucariotas. SUMO (Small ...