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A survey on the use of mice, pigs, dogs and monkeys as animal models in biomedical research in Spain
(Springernature, 2022)
[EN] Background The use of animals in biomedical science remains controversial. An individual's level of concern is generally influenced by their culture, previous or current experience with animals, and the specific animal ...
Control of Proton Exchange Membrane Fuel Cell System
(2022-06-30)
In the era of sustainable development, proton exchange membrane (PEM) fuel cell technology has shown significant potential as a renewable energy source. This thesis focuses on improving the performance of the PEM fuel cell ...
Effects of ergo-nutritional strategies on recovery in combat sports disciplines
(Aran, 2022-05)
[EN] Introduccion: Para mejorar el proceso de recuperacion en las disciplinas deportivas de combate, las estrategias ergo-nutricionales son una opcion eficaz en el entrenamiento y la competicion. Algunas de estas alternativas ...
Targeting Myotonic Dystrophy Type 1 with Metformin
(MDPI, 2022-03)
Myotonic dystrophy type 1 (DM1) is a multisystemic disorder of genetic origin. Progressive muscular weakness, atrophy and myotonia are its most prominent neuromuscular features, while additional clinical manifestations in ...
Design of protein-nanomaterial hybrids as tools for sensing, imaging and bioelectronics
(2022-06-17)
El diseño de proteínas permite construir herramientas nanotecnológicas adaptadas para su uso en campos como la biomedicina o la industria. Las proteínas de repetición CTPR son una buena opción para desarrollar nano-herramientas ...
Neddylationin Schwann cell myelination
(2022-07-26)
En esta tesis, hemos encontrado que la modificación postraduccional llamada neddylationes un regulador crítico de la mielinización en células de Schwann. El silenciamiento genético en célulasde Schwann del gen Nae1 (llamado ...
Metal-Organic Enzyme Nanogels as Nanointegrated Self-Reporting Chemobiosensors
(American Chemical Society, 2022)
[EN] A fluorometric glucose biosensor based on fine-tuned chemoenzymatic nanohybrids is herein proposed. The successful integration of an engineered glucose oxidase enzyme and an optically responsive polymeric nanogel in ...
The Association Between Puberty Timing and Body Mass Index in a Longitudinal Setting: The Contribution of Genetic Factors
(Springer, 2022)
[EN] We analyzed the contribution of genetic factors on the association between puberty timing and body mass index (BMI) using longitudinal data and two approaches: (i) genetic twin design and (ii) polygenic scores (PGS) ...
Molecular Optomechanics Approach to Surface-Enhanced Raman Scattering
(American Chemical Society, 2022)
[EN] CONSPECTUS: Molecular vibrations constitute one of the smallest mechanical oscillators available for micro-/nanoengineering. The energy and strength of molecular oscillations depend delicately on the attached specific ...