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Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
(Nature, 2022)
Antibodies against the carboxy-terminal section of the membrane-proximal external region (C-MPER) of the HIV-1 envelope glycoprotein (Env) are considered as nearly pan-neutralizing. Development of vaccines capable of ...
Molecular recognition of the HIV-1 neutralizing MPER epitope reconstituted in membranes. Contribution of lipid composition and transmembrane domain inclusion.
(2022-04-08)
GIBaren gainazalean kokatzen den Env proteina da birusaren infekzioa hasteko gertatu behar den birusaren eta itu zelularen mintzen arteko fusioa eragiten duena eta immunitate sistemarentzako eskuragarri dagoen proteina ...
Descubrimiento de nuevas dianas terapéuticas en cáncer de mama basado en el análisis de metilación del ARNm.
(2022-04-07)
N6-metiladenosina (m6A) es una de las modificaciones más abundante del ARNm presente en los organismos eucariotas. Distintos estudios han revelado que la modificación m6A está involucrada en la regulación de la mayoría de ...
Regulation of macrophage and preadipocyte proliferation and migration by C1P
(2022-03-25)
Chronic inflammatory diseases are the most significant cause of death in the world. Indeed, according to the World Health Organization (WHO), 3 out of 5 people die due to chronic inflammatory diseases such as stroke, chronic ...
Sphingomyelin: What is it good for?
(Elsevier, 2022-12)
Sphingomyelin has been considered as a merely structural lipid for many years. However, this organelle-specific lipid has many other roles, including increasing membrane molecular order, acting as a source of ceramide in ...