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Lenvatinib-Loaded Poly(lactic-co-glycolic acid) Nanoparticles with Epidermal Growth Factor Receptor Antibody Conjugation as a Preclinical Approach to Therapeutically Improve Thyroid Cancer with Aggressive Behavior
(MDPI, 2023-11-13)
Background: Lenvatinib, a tyrosine kinase inhibitor (TKI) approved for the treatment of progressive and radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC), is associated with significant adverse effects ...
Rhabdomyosarcoma: Current Therapy, Challenges, and Future Approaches to Treatment Strategies
(MDPI, 2023-11-02)
Rhabdomyosarcoma is a rare cancer arising in skeletal muscle that typically impacts children and young adults. It is a worldwide challenge in child health as treatment outcomes for metastatic and recurrent disease still ...
Health financing policies during the COVID-19 pandemic and implications for universal health care: a case study of 15 countries
(Elsevier, 2023-12)
Background The COVID-19 pandemic was a health emergency requiring rapid scal resource mobilisation to support national responses. The use of e ective health nancing mechanisms and policies, or lack thereof, a ected the ...
Pharmaceutical residues in stranded dolphins in the Bay of Biscay
(Elsevier, 2023-11-17)
There is a growing concern about the presence of pharmaceuticals on all trophic levels of the 3 aquatic environment. The presence of pharmaceuticals in the marine environment, which is the 4 final receiver of the continental ...
Suckling or non-suckling? Sensory characterization of commercialized lamb meat according to feeding
(Wiley, 2023-08-25)
Consumption of meat from suckling lambs is typical in some regions. However, sensory
differences between meat from suckling and non-suckling
lambs are barely described
in previous studies. The objectives of the present ...
Sensory evaluation of Protected Designation of origin Wines: Development of olfactive descriptive profile and references
(Elsevier, 2023-12-04)
Wines covered by PDO or PGI quality labels have specific sensory characteristics. According to EU regulations, product characteristics (including the sensory description) must be defined in the PDO technical specification ...
Altered Red Blood Cell Fatty Acid and Serum Adipokine Profiles in Subjects with Obesity
(MDPI, 2023-12-15)
Background: Adipokines, as well as the fatty acid profile of red blood cell (RBC) membranes, are known to play important roles in the development and progression of metabolic complications induced by obesity. Thus, the ...
4D Printing: The Development of Responsive Materials Using 3D-Printing Technology
(MDPI, 2023-12-07)
Additive manufacturing, widely known as 3D printing, has revolutionized the production of biomaterials. While conventional 3D-printed structures are perceived as static, 4D printing introduces the ability to fabricate ...
Antimicrobial susceptibility of Treponema pallidum subspecies pallidum: an in-vitro study
(Elsevier, 2023-10)
Background The increasing incidence of syphilis and the limitations of first-line treatment with penicillin, particularly in neurosyphilis, neonatal syphilis, and pregnancy, highlight the need to expand the therapeutic ...
Resistencia a antibióticos en dos Unidades de Medicina Intensiva de un hospital terciario: efecto de la descontaminación digestiva selectiva.
(2023-01-27)
La descontaminación digestiva selectiva (DDS) es una estrategia profiláctica basada en la administración de antibióticos tópicos no absorbibles en la mucosa oral y en el tracto gastrointestinal y de un antibiótico de amplio ...