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Endocannabinoid 2-Arachidonoylglycerol Synthesis and Metabolism at Neuronal Nuclear Matrix Fractions Derived from Adult Rat Brain Cortex
(MDPI, 2023-02-05)
In this report, we describe the kinetics characteristics of the diacylglycerol lipase-α (DGLα) located at the nuclear matrix of nuclei derived from adult cortical neurons. Thus, using high-resolution fluorescence microscopy, ...
Effectiveness of multidisciplinary treatments for fibromyalgia: a systematic review
(2023-04-04)
[EN] Introduction: The American College of Rheumatology (ACR) defines fibromyalgia (FM) as a neurologic chronic disorder. Widespread musculoskeletal pain is accompanied by a wide range of symptoms and co-morbid health ...
Speech Illusions in People at Clinical High Risk for Psychosis Linked to Clinical Outcome
(Oxford University Press, 2023-03)
Background and hypothesis
Around 20% of people at clinical high risk (CHR) for psychosis later develop a psychotic disorder, but it is difficult to predict who this will be. We assessed the incidence of hearing speech ...
Microglia and meningeal macrophages depletion delays the onset of experimental autoimmune encephalomyelitis
(SpringerNature, 2023)
In multiple sclerosis and the experimental autoimmune encephalomyelitis (EAE) model, both resident microglia and infiltrating macrophages contribute to demyelination as well as spontaneous remyelination. Nevertheless, the ...
Shedding light on motor premanifest myotonic dystrophy type 1: A molecular, muscular and central nervous system follow-up study
(Wiley, 2023-01)
Background and purpose
Myotonic dystrophy type 1 (DM1) is a hereditary and multisystemic disease that is characterized by heterogeneous manifestations. Although muscular impairment is central to DM1, a premanifest DM1 ...
Impact of parental mental illness in the attachment style of cluster B personality disorders
(2023-04-04)
[EN] Introduction: Cluster B personality disorders are the most controversial conditions in the psychopathological spectrum. Attachment seems to be a relevant factor in the development of these disorders. Emerging studies ...
Effects of the absence of TRPV1 in the expression of the cannabinoid 1 (CB1) receptor in the brain
(2023-04-05)
[EN] Though cannabinoids functions in the brain are typically associated with the activation of cannabinoid receptor 1 (CB1R), several effects depend on the activation of TRPV1, a receptor from the transient receptor ...
Mapping of plasticity and stress-related markers in acute and chronic stress in rats
(2023-04-05)
[EN] Stress is a physiological response to any kind of demand or threat that challenges the homeostasis of the organism. Although stress increases alertness and performance, excessive stress often negatively affects cognitive ...
Assisted Reproductive Techniques in Multiple Sclerosis: Recommendations from an Expert Panel
(Springer, 2023-04)
Introduction
Multiple sclerosis (MS) is mainly diagnosed in women of reproductive age. However, there is a paucity of guidelines jointly prepared by neurologists and gynaecologists on managing women with MS and the desire ...
Effect of a dietary intervention based on the Mediterranean diet on the quality of life of patients recovered from depression: Analysis of the PREDIDEP randomized trial
(Elsevier, 2023-05)
INTRODUCTION: There is substantial evidence supporting that improving diet quality leads to improved health-related quality of life (HRQoL). Our major aim was to assess the effectiveness of a Mediterranean diet-based ...