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3D-Printed Coaxial Hydrogel Patches with Mussel-Inspired Elements for Prolonged Release of Gemcitabine
(MDPI, 2021-12-13)
With the aim of fabricating drug-loaded implantable patches, a 3D printing technique was employed to produce novel coaxial hydrogel patches. The core-section of these patches contained a dopamine-modified methacrylated ...
Progress in Gelatin as Biomaterial for Tissue Engineering
(MDPI, 2022)
Tissue engineering has become a medical alternative in this society with an ever-increasing lifespan. Advances in the areas of technology and biomaterials have facilitated the use of engineered constructs for medical issues. ...
Antibacterial Activity of Small Molecules Which Eradicate Methicillin-Resistant Staphylococcus aureus Persisters
(Frontiers Media, 2022-02)
The serious challenge posed by multidrug-resistant bacterial infections with concomitant treatment failure and high mortality rates presents an urgent threat to the global health. We herein report the discovery of a new ...
Polymeric nanocarriers: A promising tool for early diagnosis and efficient treatment of colorectal cancer
(Elsevier, 2022-07)
Background: Colorectal cancer (CRC) is the third most prevalent type of cancer for incidence and second for mortality worldwide. Late diagnosis and inconvenient and expensive current diagnostic tools largely contribute to ...
Intranasal Delivery of Plasma and Platelet Growth Factors Using PRGF-Endoret System Enhances Neurogenesis in a Mouse Model of Alzheimer’s Disease
(PLoS ONE, 2013-09-19)
[EN] Neurodegeneration together with a reduction in neurogenesis are cardinal features of Alzheimer’s disease (AD) induced by a combination of toxic amyloid-β peptide (Aβ) and a loss of trophic factor support. Amelioration ...
Antibacterial smart hydrogels: New hope for infectious wound management
(Elsevier, 2022-12)
Millions of people die annually due to uncured wound infections. Healthcare systems incur high costs to treat wound infections. Tt is predicted to become more challenging due to the rise of multidrug-resistant conditions. ...
Bioprinting and biomaterials for dental alveolar tissue regeneration
(Frontiers Media, 2023)
Three dimensional (3D) bioprinting is a powerful tool, that was recently applied to
tissue engineering. This technique allows the precise deposition of cells encapsulated
in supportive bioinks to fabricate complex ...
Molecularly Imprinted Polymer-Based Sensors for the Detection of Skeletal- and Cardiac-Muscle-Related Analytes
(MDPI, 2023-06-15)
Molecularly imprinted polymers (MIPs) are synthetic polymers with specific binding sites that present high affinity and spatial and chemical complementarities to a targeted analyte. They mimic the molecular recognition ...
Cell Microencapsulation Technologies for Sustained Drug Delivery: Latest Advances in Efficacy and Biosafety
(Elsevier, 2021-07-10)
The development of cell microencapsulation systems began several decades ago. However, today few systems have been tested in clinical trials. For this reason, in the last years, researchers have directed efforts towards ...
Chitosan-based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy
(Wiley, 2023-01)
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an abundant biopolymer derived from chitin and ...