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Influence of Extracellular Matrix Components on the Expression of Integrins and Regeneration of Adult Retinal Ganglion Cells
(Public Library Science, 2015-05-27)
Purpose
Retinal ganglion cells (RGCs) are exposed to injury in a variety of optic nerve diseases including glaucoma. However, not all cells respond in the same way to damage and the capacity of individual RGCs to survive ...
Investigación pre-clínica in vitro en terapias biológicas aplicadas a patología tendinosa.
(2016-11-25)
Hoy en día, las patologías de tendón o tendinopatías suponen una gran parte de las lesiones del aparato locomotor y se asocian tanto a actividad deportiva como laboral. Los tratamientos actuales para tendinopatías son ...
RNA Localization and Local Translation in Glia in Neurological and Neurodegenerative Diseases: Lessons from Neurons
(MDPI, 2021-03-12)
Cell polarity is crucial for almost every cell in our body to establish distinct structural and functional domains. Polarized cells have an asymmetrical morphology and therefore their proteins need to be asymmetrically ...
Neuropilin-1: A feasible link between liver pathologies and COVID-19
(Baishideng Publishing Group, 2021-06-28)
[EN] The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
has a tremendous impact on the health of millions of people worldwide. Unfortunately,
those suffering from previous pathological conditions ...
Papel de la ICAM-1, COX-2 y el Receptor de Manosa en la modulación de la respuesta estromal durante la metástasis hepática por cáncer colorrectal
(2020-12-11)
La ICAM-1, la COX-2 y el Receptor de Manosa son moléculas implicadas en el desarrollo tumoral hepático por células de cáncer colorrectal. Las células tumorales colonizan el hígado formando un microambiente tumoral único, ...
Methodology and Research Protocols People with Disabilities and Other Forms of Vulnerability to the COVID-19 Pandemic: Study Protocol for a Scoping Review and Thematic Analysis
(Elsevier, 2020-12)
Objectives: To develop a protocol for a scoping review mapping as well as thematically analyzing the literature on the effect of, and responses to, the coronavirus disease 2019 (COVID-19) pandemic, focused on people with ...
Individual-based morphological brain network organization and its association with autistic symptoms in young children with autism spectrum disorder
(Wiley, 2021-07)
Individual-based morphological brain networks built from T1-weighted magnetic resonance imaging (MRI) reflect synchronous maturation intensities between anatomical regions at the individual level. Autism spectrum disorder ...
Furin Prodomain ppFurin Enhances Ca2+ Entry Through Orai and TRPC6 Channels’ Activation in Breast Cancer Cells
(MDPI, 2021-04-01)
The intracellular calcium concentration ([Ca2+]i) modulation plays a key role in the regulation of cellular growth and survival in normal cells and failure of [Ca2+]i homeostasis is involved in tumor initiation and ...
Inhibition of COX-2 Impairs Colon Cancer Liver Metastasis through Reduced Stromal Cell Reaction
(Korean Society of Applied Pharmacology, 2021-05)
Liver colonization is initiated through the interplay between tumor cells and adhesion molecules present in liver sinusoidal endothelial cells (LSECs). This crosstalk stimulates tumor COX-2 upregulation and PGE 2 secretion. ...
Longitudinal Growth Curve Trajectories of Family Dynamics after Pediatric Traumatic Brain Injury in Mexico
(MDPI, 2020-11-17)
Pediatric traumatic brain injury (TBI) represents a serious public health concern. Family members are often caregivers for children with TBI, which can result in a significant strain on familial relationships. Research is ...