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Bio-based hybrid nanocomposites as multifunctional sustainable materials for stone conservation
(Elsevier, 2023-08-23)
This study was aimed at developing a sustainable versatile bio-based epoxy-silica material to be potentially employed as hydrophobic and biocidal consolidating product in the field of stone conservation. For this purpose, ...
NMR-based metabolomics in precision medicine. Application to metabolic syndrome and COVID-19.
(2023-06-15)
La medicina de precisión debe considerarse como un enfoque innovador de la medicina tradicional ya que se centra en un tratamiento más personalizado de las patologías de los pacientes en función de sus características ...
Metabolic control of prostate cancer aggressiveness by the tumor stroma.
(2023-05-22)
El cáncer de próstata (CaP) es el segundo cáncer con mayor índice de mortalidad en hombres en la actualidad. Estos fallecimientos se deben a la falta de un buen pronóstico que permita anticipar los casos que van a recidivar. ...
An E2F7-Dependent Transcriptional Program Modulates DNA Damage Repair And Genomic Stability
(Oxford University Press, 2018-05-18)
The cellular response to DNA damage is essential for maintaining the integrity of the genome. Recent evidence has identified E2F7 as a key player in DNA damage-dependent transcriptional regulation of cell-cycle genes. ...
Pathological ATAD3 variants and perturbed cholesterol metabolism in human and fly
(2023-06-22)
Among the hundreds of nuclear-encoded components of mitochondria that have been linked to human disease, mutations in the ATAD3 gene cluster have emerged as one of the most frequent in recent years. The ATAD3 locus encodes ...
Co-Existence of blaNDM-1, blaOXA-23, blaOXA-64, blaPER-7 and blaADC-57 in a Clinical Isolate of Acinetobacter baumannii from Alexandria, Egypt
(MDPI, 2023-08-07)
The increasing rates of antimicrobial resistance among carbapenem-resistant Acinetobacter baumannii in the Middle East and North Africa are one of the major concerns for healthcare settings. We characterised the first A. ...
Phosphatidic Acid Stimulates Lung Cancer Cell Migration through Interaction with the LPA1 Receptor and Subsequent Activation of MAP Kinases and STAT3
(MDPI, 2023-06-23)
Phosphatidic acid (PA) is a key bioactive glycerophospholipid that is implicated in the regulation of vital cell functions such as cell growth, differentiation, and migration, and is involved in a variety of pathologic ...
Relationship between the Dynamics of Gross Composition, Free Fatty Acids and Biogenic Amines, and Microbial Shifts during the Ripening of Raw Ewe Milk-Derived Idiazabal Cheese
(MDPI, 2022-11-21)
This study reports for the first time the relationship between bacterial succession, characterized by high-throughput sequencing (sequencing of V3–V4 16S rRNA regions), and the evolution of gross composition, free fatty ...
Identification and functional characterization of LNCRNAS Associated with TYPE 1 Diabetes.
(2023-05-19)
Estudios de asociación de genoma completo han detectado polimorfismos asociados con el riesgo a padecer diabetes de tipo 1 (DM1) en ARN largos no codificantes (lncRNAs). Sin embargo, todavía se desconocen los mecanismos ...
Structural basis of bacterial glyeans biosynthesis and processing: ímpact in human health and disease
(2023-07-03)
El objetivo a largo plazo de nuestro grupo es estudiar a nivel molecular la estructura, la especificidad por sustrato y el mecanismo de acción de diferentes enzimas bacterianas involucradas en el reconocimiento o modificación ...