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Adenocarcinoma de Colón. Correlación de las características inmuno-histo-patológicomoleculares. La respuesta al tratamiento y la supervivencia.
(2023-03-20)
El cáncer colorrectal (CCR) es en la actualidad una de las neoplasias malignas más prevalentes,constituyendo una de las principales causas de mortalidad por cáncer en países desarrollados. En Euskadi es el tumor de mayor ...
Identification of molecular mechanisms underlying frailty and successful aging in centenarians
(2023-03-31)
El envejecimiento es un proceso sistémico, multifactorial y degenerativo caracterizado por el declive y la pérdida de capacidades físicas y mentales. La esperanza media de vida ha aumentado considerablemente en el último ...
Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies
(National Academy of Sciences, 2022-10)
Protein aggregation is a hallmark of major neurodegenerative disorders. Increasing data suggest that smaller aggregates cause higher toxic response than filamentous aggregates (fibrils). However, the size of small aggregates ...
Cardiovascular Disease, Atherosclerosis and Familial Hypercholesterolemia: From Molecular Mechanisms Causing Pathogenicity to New Therapeutic Approaches
(MDPI, 2023-04-21)
This Special Issue, “Cardiovascular Disease, Atherosclerosis and Familial Hypercholesterolemia: From Molecular Mechanisms Causing Pathogenicity to New Therapeutic Approaches”, contributes to advancing our knowledge of the ...
Metabolism in the tumor cell and beyond
(Wiley, 2023-06)
The process of cellular transformation encompasses the acquisition of key and distinctive features, commonly known as hallmarks of cancer. These hallmarks are supported by tumor-intrinsic molecular alterations, as well as ...
Characterization of Microbial Shifts during the Production and Ripening of Raw Ewe Milk-Derived Idiazabal Cheese by High-Throughput Sequencing
(MDPI, 2022-05-18)
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Characterization of Microbial Shifts during the Production and Ripening of Raw Ewe Milk-Derived Idiazabal Cheese by High-Throughput Sequencing
by Gorka Santamarina-García
* [ORCID] ...
The Sum of Plasma Fatty Acids iso16:0, iso17:0, trans11-18:1, cis9, trans11-CLA, and cis6-18:1 as Biomarker of Dairy Intake Established in an Intervention Study and Validated in the EPIC Cohort of Gipuzkoa
(MDPI, 2021-02-22)
The questioned reliability of 15:0, 17:0, and trans9-16:1 acids as biomarkers of dairy fat intake also questions the relationship between the intake of these products and their health effects. Two studies were conducted ...
Dietary fatty acid metabolism: New insights into the similarities of lipid metabolism in humans and hamsters
(Elsevier, 2022-07)
[EN] Hamsters have been long accepted as animal models to study the lipid metabolism in humans. However, very few scientific works described in detail the fatty acid (FA) composition of plasma and erythrocytes in hamsters ...
Biophysical properties of sphingolipid-deficient cell membranes
(2021-09-30)
Esta tesis pretende explorar la función de los esfingolípidos en el crecimiento celular y en la composición y las propiedades físicas de las membranas. Para ello se han utilizado células que poseen una síntesis limitada ...
Antibiotics in Dairy Production: Where Is the Problem?
(MDPI, 2022-08-01)
Antibiotics have long been used for the prevention and treatment of common diseases and for prophylactic purposes in dairy animals. However, in recent decades it has become a matter of concern due to the widespread belief ...