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Design, elaboration, characterization and evaluation of niosome formulations for gene delivery to retina and brain
(2020-12-22)
En esta tesis elaboramos y caracterizamos una nueva formulación de niosomas no virales (DP60L)basada en lípidos catiónicos DOTMA y polisorbato 60 como tensioactivo no iónico y licopeno comolípido auxiliar. Los nuevos ...
Determinants of Participation in a Post-Hospitalization Physical Exercise Program for Older Adults
(BioMed Central, 2020-10-16)
Background: Older patients often experience a decline in physical function and cognitive status after hospitalization. Although interventions involving physical exercise are effective in improving functional performance, ...
Mesenchymal stromal cells and mathematical modeling for the improvement of cell microencapsulation technologies.
(2021-01-08)
En la presente tesis doctoral se abordan aspectos relacionados con la biocompatibilidad y bioseguridad de los sistemas de microencapsulación celular para la liberación sostenida de moléculas terapéuticas.En una primera ...
Muscle and Subcutaneous Fatty Acid Composition and the Evaluation of Ageing Time on Meat Quality Parameters of Hispano-Bretón Horse Breed
(MDPI, 2021-05-15)
A full-randomized block design was used for the study of the FA composition and meat quality parameters, considering ageing time as a split-plot factor. Chemical and fatty acid composition of steaks (longissimus thoracis ...
Protein Biomarkers of Bovine Defective Meats at a Glance: Gel-Free Hybrid Quadrupole-Orbitrap Analysis for Rapid Screening
(American Chemical Society, 2021-07-07)
An understanding of biological mechanisms that could be involved in the stress response of animal cattle prior to slaughter is critical to create effective strategies aiming at the production of high-quality meat. The ...
Caspase activity in post mortem muscle and its relation to cattle handling practices
(Wiley, 2021-12)
BACKGROUND Animal handling practices are one of the factors majorly affecting animal metabolism prior to slaughter. This phenomenon increases the occurrence of meat quality defects such as dark cutting-beef, causing high ...
Proteome changes and apoptosis processes in bovine meat: methodological development and effect of animal management
(2021-07-23)
El objetivo general de esta Tesis Doctoral ha sido evaluar los procesos bioquímicos responsables de la calidad final de la carne que tienen lugar en el músculo del ganado vacuno durante la transformación del mismo en carne, ...
Gut Microbiota Induced by Pterostilbene and Resveratrol in High-Fat-High-Fructose Fed Rats: Putative Role in Steatohepatitis Onset
(MDPI, 2021-05-20)
Resveratrol and its 2-methoxy derivative pterostilbene are two phenolic compounds that occur in foodstuffs and feature hepato-protective effects. This study is devoted to analysing and comparing the metabolic effects of ...
The Sum of Plasma Fatty Acids iso16:0, iso17:0, trans11-18:1, cis9, trans11-CLA, and cis6-18:1 as Biomarker of Dairy Intake Established in an Intervention Study and Validated in the EPIC Cohort of Gipuzkoa
(MDPI, 2021-02-22)
The questioned reliability of 15:0, 17:0, and trans9-16:1 acids as biomarkers of dairy fat intake also questions the relationship between the intake of these products and their health effects. Two studies were conducted ...
The Use of Mesenchymal Stromal Cells and Tissue-Engineered Blood Vessels for Seamless Implant Integration
(2021-09-24)
In recent years, organ transplantation technology has made significant improvements regarding long-term survival, substantially decreasing the risk of graft rejection. However, with each passing year,the gap between available ...