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Design and evaluation of novel electroconductive alginate hydrogels based on graphene oxide and reduced graphene oxide with applications in tissue engineering
(2022-10-19)
El alginato es uno de los mejores biomateriales para la preparación de estos hidrogeles debido a sus excelentes propiedades, entre ellas su alta biocompatibilidad y facilidad de gelificación. Los hidrogeles de alginato han ...
Key Factors in Effective Patient-Tailored Dosing of Fluoroquinolones in Urological Infections: Interindividual Pharmacokinetic and Pharmacodynamic Variability
(MDPI, 2022-05-11)
Fluoroquinolones (FQs) are a critical group of antimicrobials prescribed in urological infections as they have a broad antimicrobial spectrum of activity and a favorable tissue penetration at the site of infection. However, ...
Outcomes associated with different vaccines in individuals with bipolar disorder and impact on the current COVID-19 pandemic- a systematic review
(Elsevier, 2022-01)
[EN] Bipolar disorder (BD) might be associated with higher infection rates of coronavirus disease (COVID-19) which in turn could result in worsening the clinical course and outcome. This may be due to a high prevalence of ...
Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects
(Elsevier, 2022-02)
P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX) resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2, HIF-1alpha, miRNAs, and long noncoding ...
The 3D Bioprinted Scaffolds for Wound Healing
(MDPI, 2022-02-21)
Skin tissue engineering and regeneration aim at repairing defective skin injuries and progress in wound healing. Until now, even though several developments are made in this field, it is still challenging to face the ...
Development and characterization of non-viral vectors based on cationic niosomes to address cystic fibrosis disease by gene therapy approach
(2022-03-17)
Gene therapy is based on the delivery of exogenous genetic material into target cells to modulate theexpression of an altered genome in order to treat a specific disease. Lipid nanocarriers, such as niosomesbased on cationic ...
Design of a New 3D Gelatin—Alginate Scaffold Loaded with Cannabis sativa Oil
(MDPI, 2022-10-25)
There is an increasing medical need for the development of new materials that could replace damaged organs, improve healing of critical wounds or provide the environment required for the formation of a new healthy tissue. ...
Lactoferrin as Immune-Enhancement Strategy for SARS-CoV-2 Infection in Alzheimer’s Disease Patients
(Frontiers Media, 2022-04-25)
Coronavirus 2 (SARS-CoV2) (COVID-19) causes severe acute respiratory syndrome. Severe illness of COVID-19 largely occurs in older people and recent evidence indicates that demented patients have higher risk for COVID-19. ...
Development of new child-friendly methods to measure food-evoked emotions holistically
(2022-07-29)
Before conducting a child-centered study, the selection of the methodology to use is of special importance since it should be adapted to their cognitive, physical, and social stage of development. On this regard, researchers ...
Does Finishing at Pasture Influence the Colour of Muscle from Suckler Bulls and Can Colour Be Used to Authenticate Their Pre-Slaughter Diet?
(MDPI, 2022-07)
[EN] The primary objective of this study was to compare the colour of muscle from bulls finished at pasture or indoors on a high concentrate diet. The ancillary objectives were to identify possible explanations for any ...