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Clinical progress in MSC-based therapies for the management of severe COVID-19.
(Elsevier, 2022-12)
Considering the high impact that severe Coronavirus disease 2019 (COVID-19) cases still pose on public health and their complex pharmacological management, the search for new therapeutic alternatives is essential. Mesenchymal ...
Development of a microencapsulated functional ingredient formulated with the neurotransmitter GABA and the Lactiplantibacillus plantarum K16 produced through biotechnological processes
(2023-01-18)
This PhD thesis has developed a new functional ingredient characterised by the novelty of combining anew L. plantarum K16 strain, isolated from the fermented food Kimchi, with the postbiotic metaboliteGABA produced by a ...
Heltze denborak zaldi haragian duen eragina: ikuspegi instrumentala eta sentsoriala
(2022-07-21)
El objetivo de la presente Tesis Doctoral ha sido ha sido investigar el efecto del tiempo de maduración sobre los parámetros de calidad de la carne de caballo, utilizando tanto metodologías instrumentales como sensoriales. ...
Anti-Obesity Effects of Isorhamnetin and Isorhamnetin Conjugates
(MDPI, 2022-12-24)
Isorhamnetin is a plant-derived secondary metabolite which belongs to the family of flavonoids. This review summarises the main outcomes described in the literature to date, regarding the effects of isorhamnetin on obesity ...
An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice
(MDPI, 2022-12-30)
Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy causing progressive vision loss. It is accompanied by chronic and sustained inflammation, including M1 microglia activation. This study evaluated the ...
Modificación del proceso de oxidación de aceites comestibles poliinsaturados por efecto de su enriquecimiento en algunos compuestos con potencial capacidad antioxidante y por efecto de la temperatura.
(2023-02-17)
En la presente memoria para optar al grado de doctor se presenta un resumen de los resultados y las conclusiones más importantes extraídas de los estudios llevados a cabo con el fin de elucidar el efecto que tiene, por un ...
Chitosan-based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy
(Wiley, 2023-01)
Green chemistry has been a growing multidisciplinary field in recent years showing great promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an abundant biopolymer derived from chitin and ...
Caracterización clínico-genética de pacientes con iPPSD y aproximación a la transfección de células madre mesenquimales derivadas de orina mediante niosomas catiónicos
(2022-03-02)
El término iPPSD (inactivating PTH/PTHrP signalling disorder) hace referencia a un grupo de enfermedades (epi)genéticas raras caracterizadas todas ellas por una disfunción en la cascada de señalización de PTH/PTHrP. En la ...
Three-dimensional printing as a cutting-edge, versatile and personalizable vascular stent manufacturing procedure:Toward tailor-made medical devices
(WHIOCE, 2023)
Vascular stents (VS) have revolutionized the treatment of cardiovascular diseases, as evidenced by the fact that the implantation of VS in coronary artery disease (CAD) patients has become a routine, easily approachable ...
Relationship between changes in microbiota induced by resveratrol and its anti-diabetic effect on type 2 diabetes
(Frontiers Media, 2023-01)
Although a general healthy gut microbiota cannot be defined due to numerous internal and external individual factors, such as sex, age, ethnicity, genetics, environment, diet and drugs affect its composition, certain ...