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Calcium Sensing Receptor, Calcium Binding Proteins and Astrocytic Changes in Alzheimers Disease.
(2017-05-31)
La enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa caracterizada por la pérdida de memoria y disfunciones cognitivas, entre las cuales se incluyen problemas del lenguaje, desorientación, pérdida de la ...
Factors associated with chronic pain in patients with bipolar depression: a cross-sectional study
(BioMed Central, 2013-04-15)
Background: While pain is frequently associated with unipolar depression, few studies have investigated the link between pain and bipolar depression. In the present study we estimated the prevalence and characteristics of ...
Birth Weight, Working Memory and Epigenetic Signatures in IGF2 and Related Genes: A MZ Twin Study
(Public Library Science, 2014-08-29)
Neurodevelopmental disruptions caused by obstetric complications play a role in the etiology of several phenotypes associated with neuropsychiatric diseases and cognitive dysfunctions. Importantly, it has been noticed that ...
SU-8 microprobes for biomedical applications
(2014-01-30)
[ES]La presente tesis doctoral aborda el diseño, fabricación, encapsulado, y caracterización de microagujas de SU-8 para aplicaciones médicas. En la actualidad existe una amplia variedad de agujas para el registro, ...
Molecular Components and Functions of the Endocannabinoid System in Mouse Prefrontal Cortex
(Public Library of Science, 2007-08-08)
Background. Cannabinoids have deleterious effects on prefrontal cortex (PFC)-mediated functions and multiple evidences link the endogenous cannabinoid (endocannabinoid) system, cannabis use and schizophrenia, a disease in ...
A Model of Ischemia-Induced Neuroblast Activation in the Adult Subventricular Zone
(Public Library of Science, 2009-04-23)
We have developed a rat brain organotypic culture model, in which tissue slices contain cortex-subventricular zone-striatum regions, to model neuroblast activity in response to in vitro ischemia. Neuroblast activation has ...
Antioxidant defense system and family environment in adolescents with family history of psychosis
(BioMed Central, 2012-11-16)
[EN] Our objective was to determine antioxidant defence activity in healthy controls (HC) and healthy unaffected second-degree relatives of patients with early onset psychosis (HC-FHP),and to assess its relationship with ...
A neural extracellular matrix-based method for in vitro hippocampal neuron culture and dopaminergic differentiation of neural stem cells
(BioMed Central, 2013)
Background: The ability to recreate an optimal cellular microenvironment is critical to understand neuronal
behavior and functionality in vitro. An organized neural extracellular matrix (nECM) promotes neural cell ...
Distribution of stem cells inside induced gliomas by ethyl-nitrosurea
(2014-12-19)
Los gliomas son tumores del sistema nervioso central de carácter difuso y con una alta vascularización. Las células que guían el crecimiento y expansión tumoral son las células madre tumorales que hay en el interior ...
Increased physical activity is not enough to recover astrocytic population from dark-rearing. Synergy with multisensory enrichment is required
(Frontiers Research Foundation, 2013-10-04)
Elimination of sensory inputs (deprivation) modifies the properties of the sensory cortex and serves as a model for studying plasticity during postnatal development. Many studies on the effects of deprivation have been ...