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Now showing items 131-140 of 209
Sobredosificación de benzodiazepinas en ancianos y caídas: implicaciones clínicas y económicas.
(2020-03-02)
Las Benzodiacepinas/Z son unos fármacos ampliamente utilizados en la población anciana. Las pautas de prescripción no siempre se adecúan a las recomendaciones de las guías clínicas publicadas. Las consecuencias derivadas ...
Unraveling the role of astrocytes in the onset and spread of Parkinson's Disease: Important contributors to neurodegeneration.
(2020-02-28)
La enfermedad de Parkinson (EP) se caracteriza principalmente por la presencia de inclusiones citoplasmáticas llamadas cuerpos de Lewy, cuyo principal componente es la ¿-sinucleína y la pérdida de neuronas dopaminérgicas ...
Evolución del diagnóstico molecular de la distrofia facioescapulohumeral: la historia (inacabada) de una cohorte histórica
(2021-06-23)
La distrofia facioescapulohumeral (DFEH1, OMIM 158900) es la tercera enfermedad muscular más común, después de la distrofia de Duchenne y la distrofia miotónica, (Padberg, 1982) cuya prevalencia se estima en 1:20.000 ...
The Role of Premorbid IQ and Age of Onset as Useful Predictors of Clinical, Functional Outcomes, and Recovery of Individuals with a First Episode of Psychosis
(MDPI, 2021-06-02)
Background: premorbid IQ (pIQ) and age of onset are predictors of clinical severity and long-term functioning after a first episode of psychosis. However, the additive influence of these variables on clinical, functional, ...
Estudio de la diversidad de variantes polimórficas de las proteínas del prion de cérvidos, su capacidad de malplegamiento e influencia sobre la emergencia de cepas con características distintivas.
(2022-11-18)
Las encefalopatías espongiformes transmisibles o enfermedades priónicas son un conjunto de desórdenes neurodegenerativos letales que afectan a los mamíferos. El agente causal de estas enfermedades es el prion o PrPSc, la ...
Microglial phagocytosis form development to neurodegenerative diseases
(2021-09-30)
a microglía es el macrófago residente del sistema nervioso central (SNC). Estos centinelas cerebrales "escanean" continuamente el parénquima cerebral con sus procesos delgados, largos y ramificados que ayudan a mantener ...
Cross-Validation of Predictive Equation for Cardiorespiratory Fitness by Modified Shuttle Walk Test in Adults with Schizophrenia: A Secondary Analysis of the CORTEX-SP Study
(MDPI, 2021-10-29)
Cardiorespiratory fitness (CRF) can be direct or estimated from different field tests. The Modified Shuttle Walk Test (MSWT) is suitable for all levels of function, allowing a peak response to be elicited. Therefore, we ...
Neurocognitive, social cognitive, and clinical predictors of creativity in schizophrenia
(Pergamon-Elsevier, 2020-10)
Background: Creativity is considered an essential human accomplishment and a key component for daily life problem solving. It has been suggested that impairment in working memory, cognitive flexibility, and theory of mind ...
The impact of creativity on functional outcome in schizophrenia: a mediational model
(Springer, 2021-02-26)
Functional impairment remains one of the most challenging issues for treatment in schizophrenia. However, previous studies have mainly focused on the negative impact of symptoms excluding variables that could positively ...
Cannabinoid Control of Olfactory Processes: The Where Matters
(MDPI, 2020-04-16)
Olfaction has a direct influence on behavior and cognitive processes. There are different neuromodulatory systems in olfactory circuits that control the sensory information flowing through the rest of the brain. The presence ...