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Lithium levels and lifestyle in patients with bipolar disorder: a new tool for self-management
(Springer, 2023-03)
BACKGROUND: Patients should get actively involved in the management of their illness. The aim of this study was to assess the influence of lifestyle factors, including sleep, diet, and physical activity, on lithium levels ...
Combining imaging mass spectrometry and immunohistochemistry to analyse the lipidome of spinal cord inflammation
(Springer Nature, 2024-02)
Inflammation is a complex process that accompanies many pathologies. Actually, dysregulation of the inflammatory process is behind many autoimmune diseases. Thus, treatment of such pathologies may benefit from in-depth ...
Areas of interest and sentiment analysis towards second generation antipsychotics, lithium and mood stabilizing anticonvulsants: Unsupervised analysis using Twitter
(Elsevier, 2024-04)
Background
Severe mental disorders like Schizophrenia and related psychotic disorders (SRD) or Bipolar Disorder (BD) require pharmacological treatment for relapse prevention and quality of life improvement. Yet, treatment ...
A nonlinear meccano for Alzheimer's emergence by amyloid β-mediated glutamatergic hyperactivity
(Elsevier, 2024-05)
The pathophysiological process of Alzheimer's disease (AD) is believed to begin many years before the formal diagnosis of AD dementia. This protracted preclinical phase offers a crucial window for potential therapeutic ...
Oocyte electroporation prior to in vitro fertilization is an efficient method to generate single, double, and multiple knockout porcine embryos of interest in biomedicine and animal production
(Elsevier, 2024-04)
Genetically modified pigs play a critical role in mimicking human diseases, xenotransplantation, and the development of pigs resistant to viral diseases. The use of programmable endonucleases, including the CRISPR/Cas9 ...
Mecanismos de regulación de la actividad del retrómero.
(2024-01-30)
Las células están constantemente moviendo material como parte de su inherente actividad e interacciones con el entorno. La red endosomal es un foco de redistribución de moléculas. Esta red recibe proteínas transmembrana, ...
Sexually transmitted infections, sexual life and risk behaviours of people living with schizophrenia: systematic review and meta-analysis
(Cambridge University Press, 2024)
Background
Sexually transmitted infections (STIs), along with sexual health and behaviour, have received little attention in schizophrenia patients.
Aims
To systematically review and meta-analytically characterise ...
Blocking ATP signaling and ROS generation preserves neurogenesis and network activity In epileptogenesis In hippocampal organotypic slice cultures.
(2024-01-26)
Epilepsy is a common neurological disorder, which lacks a comprehensive understanding of epileptogenesis. Temporal lobe epilepsy (TLE) in particular, often involves the hippocampus, with gliosis and abnormal neurogenesis. ...
The effect of omega-3 fatty acids on alcohol-induced damage
(Frontiers Media, 2023-04)
Alcohol is the most widely consumed psychoactive substance in the world that has a severe impact on many organs and bodily systems, particularly the liver and nervous system. Alcohol use during pregnancy roots long-lasting ...
Violence in first-episode psychosis: evidence from an early intervention in psychosis programme
(Cambridge University Press, 2023-09)
Background
Psychotic disorders are frequently associated with a public perception of dangerousness and belligerence. This situation has contributed to the social stigmatisation of people with severe mental illness and ...