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Quantifying Knowledge of Alzheimer's Disease: an Analysis of the Psychometric Properties of the Alzheimer's Disease Knowledge Scale
(Springer, 2021-06)
Introduction: The Alzheimer's Disease Knowledge Scale (ADKS) is one of the most popular instruments for assessing a person's knowledge regarding Alzheimer's disease (AD). The objective of this study was to explore ADKS ...
Revisiones sistemáticas y meta-análisis en modelos animales para la investigación traslacional de patologías psiquiátricas.
(2021-09-16)
El trabajo se centra en el estudio de la eficacia de antinflamatorios en modelos animales de depresión como acercamiento a la investigación traslacional en su posible aplicación como intervención terapéutica en depresión. ...
True-color 3D rendering of human anatomy using surface-guided color sampling from cadaver cryosection image data: A practical approach Jon Jatsu Azkue
(Wiley, 2022-08)
Three-dimensional computer graphics are increasingly used for scientific visualization and for communicating anatomical knowledge and data. This study presents a practical method to produce true-color 3D surface renditions ...
Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila
(Elsevier, 2022-07)
[EN] Recruitment of stem cells is crucial for tissue repair. Although stem cell niches can provide important signals, little is known about mechanisms that coordinate the engagement of disseminated stem cells across an ...
Never-resting microglia: physiological roles in the healthy brain and pathological implications
(Frontiers Research Foundation, 2014-08-15)
Microglia are largely known as the major orchestrators of the brain inflammatory response. As such, they have been traditionally studied in various contexts of disease, where their activation has been assumed to induce a ...
Generación de distintas cepas de priones recombinantes como herramienta para el estudio del alplegamiento espontáneo en las enfermedades priónicas
(2021-09-17)
La isoforma malplegada (PrPSc) de la proteína del prion celular (PrPC), es el agente causal de las Encefalopatías Espongiformes Transmisibles (EET), un conjunto de desórdenes neurodegenerativos mortales que afectan a ...
2-Arakidonilglizerol endokannabinoidearen sintesi- eta degradazio-makineria neuronaren nukleoan: Diazilglizerol Lipasa alfa-ren konpartimentazioa eta aktibitate entzimatikoa
(2017-09-29)
Ikerketa lan honetan, zatikapen azpizelularra, Western blot eta fluoreszentzia mikroskopia bidez, diazilglizerol lipasa ¿-ren (DAGL¿) presentzia frogatu dugu arratoi helduaren garun-kortexetik isolatutako nukleoetan. ...
The Influence of Oxytocin and Prolactin During a First Episode of Psychosis: The Implication of Sex Differences, Clinical Features, and Cognitive Performance
(Oxford University Press, 2022-08)
Background Approximately 3% of the population suffers a first episode of psychosis (FEP), and a high percentage of these patients subsequently relapse. Because the clinical course following a FEP is hard to predict, it is ...
Examining the variability of neurocognitive functioning in individuals at clinical high risk for psychosis: a meta-analysis
(Springer, 2022-05-12)
This study aims to meta-analytically characterize the presence and magnitude of within-group variability across neurocognitive functioning in young people at Clinical High-Risk for psychosis (CHR-P) and comparison groups. ...
Metabolic polygenic risk scores effect on antipsychotic-induced metabolic dysregulation: A longitudinal study in a first episode psychosis cohort
(Elsevier, 2022-06)
[EN] Objective: Metabolic syndrome is a health-threatening condition suffered by approximately one third of schizophrenia patients and largely attributed to antipsychotic medication. Previous evidence reports a common ...