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Mostrando ítems 281-290 de 493
Estudio de la diversidad de variantes polimórficas de las proteínas del prion de cérvidos, su capacidad de malplegamiento e influencia sobre la emergencia de cepas con características distintivas.
(2022-11-18)
Las encefalopatías espongiformes transmisibles o enfermedades priónicas son un conjunto de desórdenes neurodegenerativos letales que afectan a los mamíferos. El agente causal de estas enfermedades es el prion o PrPSc, la ...
Identifying alterations in RNA metabolism and translation dynamics of oligodendrocytes in Alzheimer's disease
(2023-04-03)
La degeneración de la mielina y la pérdida de sustancia blanca son eventos tempranos en la enfermedad de Alzheimer (EA) que conducen a déficits cognitivos. Uno de los rasgos distintivos de la EA es la presencia de agregados ...
Cerebrolysin Attenuates Exacerbation of Neuropathic Pain, Blood-spinal Cord Barrier Breakdown and Cord Pathology Following Chronic Intoxication of Engineered Ag, Cu or Al (50–60 nm) Nanoparticles
(Springer, 2023-01)
Neuropathic pain is associated with abnormal sensations and/or pain induced by non-painful stimuli, i.e., allodynia causing burning or cold sensation, pinching of pins and needles like feeling, numbness, aching or itching. ...
Mortality Risks after Two Years in Frail and Pre-Frail Older Adults Admitted to Hospital
(MDPI, 2023-04-24)
Background: Frailty is characterized by a progressive decline in the physiological functions of multiple body systems that lead to a more vulnerable condition, which is prone to the development of various adverse events, ...
Microglial phagocytosis form development to neurodegenerative diseases
(2021-09-30)
a microglía es el macrófago residente del sistema nervioso central (SNC). Estos centinelas cerebrales "escanean" continuamente el parénquima cerebral con sus procesos delgados, largos y ramificados que ayudan a mantener ...
Cross-Validation of Predictive Equation for Cardiorespiratory Fitness by Modified Shuttle Walk Test in Adults with Schizophrenia: A Secondary Analysis of the CORTEX-SP Study
(MDPI, 2021-10-29)
Cardiorespiratory fitness (CRF) can be direct or estimated from different field tests. The Modified Shuttle Walk Test (MSWT) is suitable for all levels of function, allowing a peak response to be elicited. Therefore, we ...
Evaluación del efecto de la regulación de la ruta de Wnt y mTOR en la distrofia muscular de cinturas R1 asociada a calpaína 3
(2023-07-17)
La distrofia muscular de cinturas R1 asociada a calpaína 3 (LGMDR1) o calpainopatía, es una distrofia muscular con herencia autosómico recesiva causada por mutaciones del gen CAPN3. El presente trabajo de investigación ...
Neurocognitive, social cognitive, and clinical predictors of creativity in schizophrenia
(Pergamon-Elsevier, 2020-10)
Background: Creativity is considered an essential human accomplishment and a key component for daily life problem solving. It has been suggested that impairment in working memory, cognitive flexibility, and theory of mind ...
Mediating role of cognition and social cognition on creativity among patients with schizophrenia and healthy controls: Revisiting the Shared Vulnerability Model
(Wiley, 2019-12)
Aim As suggested by the Shared Vulnerability Model, impairment in executive functions could lead to worse creative performance among individuals with schizophrenia. Another impaired function in schizophrenia, previously ...
The impact of creativity on functional outcome in schizophrenia: a mediational model
(Springer, 2021-02-26)
Functional impairment remains one of the most challenging issues for treatment in schizophrenia. However, previous studies have mainly focused on the negative impact of symptoms excluding variables that could positively ...