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Endocannabinoid 2-Arachidonoylglycerol Synthesis and Metabolism at Neuronal Nuclear Matrix Fractions Derived from Adult Rat Brain Cortex
(MDPI, 2023-02-05)
In this report, we describe the kinetics characteristics of the diacylglycerol lipase-α (DGLα) located at the nuclear matrix of nuclei derived from adult cortical neurons. Thus, using high-resolution fluorescence microscopy, ...
Análisis exploratorio de la influencia sobre dimensiones de personalidad de polimorfismos genéticos funcionales de la catecol-o-metiltransferasa, el transportador de serotonina y la monoamino oxidasa-A, y su interacción con variables ambientales adversas. Un estudio en pacientes con trastornos de la personalidad y controles sanos
(2019-01-22)
Se estudia el efecto de polimorfismos genéticos funcionales de la catecol-o-metil transferasa (COMT), del trasportador de serotonina y de la monoamino oxidasa-A (MAO-A) sobre dimensiones de la personalidad, según el modelo ...
Genetics of adult attachment: An updated review of the literature
(Baishideng Publishing Group, 2021-09-19)
Attachment style, which has been theorized to be rooted in childhood bonding experiences, influences adult cognitive, emotional and interpersonal functioning. Despite its relationship with early experiences, research ...
Effectiveness of multidisciplinary treatments for fibromyalgia: a systematic review
(2023-04-04)
[EN] Introduction: The American College of Rheumatology (ACR) defines fibromyalgia (FM) as a neurologic chronic disorder. Widespread musculoskeletal pain is accompanied by a wide range of symptoms and co-morbid health ...
Speech Illusions in People at Clinical High Risk for Psychosis Linked to Clinical Outcome
(Oxford University Press, 2023-03)
Background and hypothesis
Around 20% of people at clinical high risk (CHR) for psychosis later develop a psychotic disorder, but it is difficult to predict who this will be. We assessed the incidence of hearing speech ...
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project
(Elsevier Science INC, 2019-10)
Introduction: Large variability among Alzheimer's disease (AD) cases might impact genetic discoveries and complicate dissection of underlying biological pathways.
Methods: Genome Research at Fundacio ACE (GR@ACE) is a ...
Increased expression of cystine/glutamate antiporter in multiple sclerosis
(BioMed Central, 2011-06-03)
Background: Glutamate excitotoxicity contributes to oligodendrocyte and tissue damage in multiple sclerosis (MS). Intriguingly, glutamate level in plasma and cerebrospinal fluid of MS patients is elevated, a feature which ...
GABAergic and Cortical and Subcortical Glutamatergic Axon Terminals Contain CB1 Cannabinoid Receptors in the Ventromedial Nucleus of the Hypothalamus
(Public Library of Science, 2011-10)
Background: Type-1 cannabinoid receptors (CB1R) are enriched in the hypothalamus, particularly in the ventromedial hypothalamic nucleus (VMH) that participates in homeostatic and behavioral functions including food intake. ...
Assessment of Psychiatric Symptomatology in Bilingual Psychotic Patients: A Systematic Review and Meta-Analysis
(MDPI, 2020-06-10)
Language plays an important role in psychiatric conditions. Language disturbances are core symptoms of psychiatric ailments, and language is the main diagnostic tool to assess psychopathological severity. Although the ...
Visualization by High Resolution Immunoelectron Microscopy of the Transient Receptor Potential Vanilloid-1 at Inhibitory Synapses of the Mouse Dentate Gyrus
(Public Library Science, 2015-03-16)
We have recently shown that the transient receptor potential vanilloid type 1 (TRPV1), a non-selective cation channel in the peripheral and central nervous system, is localized at postsynaptic sites of the excitatory ...