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Trastornos disautonómicos en la enfermedad de Parkinson
(2023-12-18)
La enfermedad de Parkinson es una enfermedad crónica neurodegenerativa sin tratamiento curativo en la actualidad. En ausencia de un tratamiento eficaz que frene, module o cure la enfermedad, el impacto en la calidad de ...
Suicidal behavior and deliberate self-harm: A major challenge for youth residential care in Spain
(Elsevier, 2024-03)
The aim of this study was to characterize and determine the incidence of suicidal behavior and deliberate self-harm among youth in residential care in Spain, and to explore the perceived knowledge and competence of direct ...
Planificación familiar en hombres y mujeres con esclerosis múltiple. Análisis del Registro Andaluz de embarazos en pacientes con esclerosis mútliple (RAEEM)
(2023-12-13)
La esclerosis múltiple es una enfermedad neurológica, crónica, degenerativa, autoinmune. Considerada lasegunda causa más frecuente de discapacidad en el adulto joven. En España se estima que hay unos55.000 casos. Se ...
Association of retinal neurodegeneration with the progression of cognitive decline in Parkinson’s disease
(Nature, 2024-01)
Retinal thickness may serve as a biomarker in Parkinson’s disease (PD). In this prospective longitudinal study, we aimed to determine if PD patients present accelerated thinning rate in the parafoveal ganglion cell-inner ...
Pharmacogenetics of MicroRNAs and MicroRNAs Biogenesis Machinery in Pediatric Acute Lymphoblastic Leukemia
(Public Library Science, 2014-03-10)
Despite the clinical success of acute lymphoblastic leukemia (ALL) therapy, toxicity is frequent. Therefore, it would be useful to identify predictors of adverse effects. In the last years, several studies have investigated ...
Age‐related cognitive decline in myotonic dystrophy type 1: An 11‐year longitudinal follow‐up study
(Wiley, 2020-03)
Background Myotonic dystrophy type 1 (DM1) is an inherited multi-systemic disease involving the central nervous system (CNS) and is consequently characterized by a range of cognitive impairments. However, whether this ...
Ejercicio físico combinado en personas con esquizofrenia: estudio Cortex-SP
(2024-02-01)
Objetivos: los objetivos principales de esta tesis doctoral en personas con esquizofrenia (SZ) fueron: 1) determinar algunos marcadores físicos, fisiológicos y bioquímicos clave del estado de salud, incluida la calidad del ...
Evolution of pallial high-order sensory processing circuits.
(2024-01-12)
Understanding the appearance of the neocortex in evolution requires the study of its stereotyped sensory processing circuits andtheir formation during embryonic development. These circuits appear in sensory structures of ...
Retinal thickness as a biomarker of cognitive impairment in manifest Huntington’s disease
(Springer Nature, 2023)
Background
Cognitive decline has been reported in premanifest and manifest Huntington’s disease but reliable biomarkers are lacking. Inner retinal layer thickness seems to be a good biomarker of cognition in other ...
Isolation and Differentiation of Neurons and Glial Cells from Olfactory Epithelium in Living Subjects
(Springer Nature, 2023)
The study of psychiatric and neurological diseases requires the substrate in which the disorders occur, that is, the nervous tissue. Currently, several types of human bio-specimens are being used for research, including ...