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Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis
(BioMed Central, 2008-10)
Background: The recruitment of vascular stromal and endothelial cells is an early event occurring during cancer cell growth at premetastatic niches, but how the microenvironment created by the initial three-dimensional ...
Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18
(BioMed Central, 2011-05)
Background: Implantation and growth of metastatic cancer cells at distant organs is promoted by inflammation-dependent mechanisms. A hepatic melanoma metastasis model where a majority of metastases are generated via ...
α2,3-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo
(Public Library of Science, 2010-09-01)
Background: Cell surface sialylation is emerging as an important feature of cancer cell metastasis. Sialyltransferase expression has been reported to be altered in tumours and may account for the formation of sialylated ...
El plasma rico en factores de crecimiento como alternativa terapéutica en el ojo seco y en defectos epiteliales persistentes
(2015-10-30)
El objetivo de la presente Tesis es evaluar la eficacia y seguridad del Plasma Rico en Factores de Crecimiento en dos de las patologías más importantes de la superficie ocular y que más atención requieren en la práctica ...
Efecto antitumoral de la terfenadina, antagonista del receptor H1 de la histamina, mediado por el complejo I mitocondrial
(2015-07-10)
El cáncer es una de las principales causas de muerte a escala mundial y un problema de salud prioritario. Cada año la incidencia del cáncer aumenta, y a pesar de que la mortalidad disminuye gracias a los avances en el ...
Implicación de Anexina A5 en la progresión maligna del melanoma humano. Valor pronóstico
(2015-07-10)
El melanoma cutáneo es un tumor maligno que se origina a partir de la transformación maligna de los melanocitos de la epidermis. El interés por este tumor es cada vez mayor, ya que la incidencia de esta neoplasia crece de ...
Caregiver Characteristics of Adults with Acute Traumatic Brain Injury in the United States and Latin America
(MDPI, 2022-05)
Objectives: To compare characteristics of caregivers of adults with acute traumatic brain injury (TBI) in the U.S. and Latin America (Mexico and Colombia). Design: Secondary data analysis of two cohorts. Cohort 1: ...
Transscleral Cyclophotocoagulation for the Treatment of Uncontrolled Glaucoma in a Boston Keratoprosthesis Type II Patient
(Karger, 2022)
[EN] Postoperative endoscopic cyclophotocoagulation (CPC) for the treatment of glaucoma in patients with Boston keratoprosthesis type II (BKPro II) was first described in 2017 by Poon et al. (Endoscopic cyclophotocoagulation ...
Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling
(BioMed Central, 2011)
Background
The wounding response relies on tightly regulated crosstalk between recruited fibroblasts and the collagenous extracellular matrix (ECM). Discoidin domain receptor 2 (DDR2) is a tyrosine kinase receptor for ...
Interacciones entre las células madre pluripotentes del carcinoma embrionario y las células mioides peritubulares del testículo
(2015-09-08)
Los túbulos seminíferos del testículo están constituidos por un lumen central, formadopor dos tipos celulares diferentes: las células de Sertoli y las células espermatogénicasque conforman el epitelio seminífero. Este ...