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Now showing items 111-116 of 116
Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach
(MDPI, 2021-06-11)
Heat shock protein (Hsp) synthesis is upregulated in a wide range of cancers to provide the appropriate environment for tumor progression. The Hsp110 and Hsp70 families have been associated to cancer cell survival and ...
Nanostructured scaffolds based on bioresorbable polymers and graphene oxide induce the aligned migration and accelerate the neuronal differentiation of neural stem cells
(Elsevier, 2021-01-31)
Within the field of neural tissue engineering, there is a huge need for the development of materials that promote the adhesion, aligned migration and differentiation of stem cells into neuronal and supportive glial cells. ...
Analysis of different strategies for in vitro diagnosis of human humoral biomarkers based on solid support immobilization
(2023-11-03)
The study of biomarkers and their detection in human fluids represents one of the best ways to improve the diagnosis and prevention of diseases. The use of human fluids for biomarker analysis can facilitate a friendly and ...
Novel proteomic and lipidomic biomarkers for limbal epithelial stem cell identification and corneal transplant monitoring
(2022-07-28)
El objeto de esta tesis doctoral ha sido la caracterización proteómica y lipidómica de cinco poblaciones celulares de la córnea humana para la identificación de nuevos biomarcadores de cada tipo celular. Además, se han ...
The Prevention of Ischemia-Reperfusion Injury in Elderly Rats after Lower Limb Tourniquet Use
(MDPI, 2022-09-28)
Background: Lower limb ischemia-reperfusion injury (IRI-LL) is a common major complication of orthopedic surgery, especially in elderly patients. It has previously been demonstrated that folinic acid (FA) reduced IRI-LL ...
The role of Eudragit® as a component of hydrogel formulations for medical devices
(RSC, 2023)
Over the last decade, significant progress has been made in developing hydrogels as medical devices. By physically cross-linking pharmaceutically approved polymers into three-dimensional matrices, we can ensure their ...