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Interaction of the LC3/GABARAP autophagy proteins with membranes: Exploring the effects of ceramide
(2023-07-21)
La macroautofagia es un proceso que ocurre en los organismos eucariotas, se caracteriza por la formación del autofagosoma, una estructura de doble membrana encargada de rodear los componentes celulares que se degradan ...
Lipid-protein interactions in autophagy: Exploring the role of LC3/GABARAP-family members
(2022-07-19)
La autofagia es una vía de degradación conservada entre los eucariotas caracterizada por la formación de una vesícula de doble membrana (autofagosoma) alrededor de lo que se quiere degradar para su posterior eliminación ...
Patches and Blebs: A Comparative Study of the Composition and Biophysical Properties of Two Plasma Membrane Preparations from CHO Cells
(MDPI, 2020-04-10)
This study was aimed at preparing and characterizing plasma membranes (PM) from Chinese Hamster Ovary (CHO) cells. Two methods of PM preparation were applied, one based on adhering cells to a poly-lysine-coated surface, ...
Exploring the transcriptional hallmarks of aging using single-cell RNA sequencing
(2023-11-14)
Aging is associated with a series of phenotypic changes at the cellular level, including changes in gene expression. In recent years, aged tissues have been reported to present an increase in transcriptional noise or ...
Non-radical photopolymerizable systems; towards sustainable applications in light-mediated additive manufacturing
(2023-11-13)
Las tecnologías de fabricación han sido transformadas por los avances en la fabricación aditiva. Esta técnica revolucionaria minimiza el desperdicio, permite la producción de estructuras complejas y producción a medida. ...
Artificial Intelligence-based contributions to the detection of threats against information systems
(2023-11-20)
Esta tesis se centra en identificar los factores que hacen poco realistas las propuestas de detección de ataques en red (NIDS) y detectores de malware en Android. En el área de NIDS, se han estudiado la aplicabilidad en ...
A generic multi-robot architecture for mobile manipulator robots and its integration in the smart factory
(2023-11-03)
Esta Tesis Doctoral se centra en dar solución a dos de las principales demandas de los sistemas de fabricación flexibles en el ámbito de los Robots Móviles de Manipulación (MMRs).Por un lado, se presenta Robotframework, ...
Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
(Nature, 2022)
Antibodies against the carboxy-terminal section of the membrane-proximal external region (C-MPER) of the HIV-1 envelope glycoprotein (Env) are considered as nearly pan-neutralizing. Development of vaccines capable of ...
Synthesis of advanced bio-based green materials from renewable biopolymers
(Elsevier, 2021-01-30)
Polymeric materials such as hydrogels have become necessary in our daily lives. Hydrogels are three-dimensionally cross-linked polymeric networks that can absorb large amounts of water. Thanks to their properties, hydrogels ...
Effects of Early-Childhood-Based Interventions Influencing Bones: A Systematic Review
(MDPI, 2023-12-20)
A healthy lifestyle from early childhood is a crucial factor that influences bone-related factors in adulthood. In this context, physical education or psychomotricity from early childhood is an important opportunity to ...