Search
Now showing items 51-60 of 87
Neuroprotection of retinal ganglion cells by Müller Glia in vitro in health and disease
(2019-10-07)
Las células ganglionares de la retina (RGCs) son las únicas neuronas aferentes de la retina y transmiten la información visual al cerebro a través de sus axones, que forman el nervio óptico y su muerte causa una ceguera ...
Effects of Adult Müller Cells and Their Conditioned Media on the Survival of Stem Cell-Derived Retinal Ganglion Cells
(MDPI, 2020-07-22)
Retinal neurons, particularly retinal ganglion cells (RGCs), are susceptible to the degenerative damage caused by different inherited conditions and environmental insults, leading to irreversible vision loss and, ultimately, ...
A Customized Pigmentation SNP Array Identifies a Novel SNP Associated with Melanoma Predisposition in the SLC45A2 Gene
(Public Library of Science, 2011-04-29)
As the incidence of Malignant Melanoma (MM) reflects an interaction between skin colour and UV exposure, variations in genes implicated in pigmentation and tanning response to UV may be associated with susceptibility to ...
Estimation of preterm labor immediacy by nonlinear methods
(Public Library Science, 2017-06-01)
Preterm delivery affects about one tenth of human births and is associated with an increased perinatal morbimortality as well as with remarkable costs. Even if there are a number of predictors and markers of preterm delivery, ...
Development of new methods in biomedical engineering for brain connectivity biomarkers in epilepsy and other pathological conditions
(2018-05-07)
The aim of this thesis is to humbly explore the application of diverse methodologies and theories comingfrom Computer Sciences, Mathematics and Physics in the field of neurosciences, with an special focus onneurodegenerative ...
Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma
(Public Library Science, 2014-04-17)
Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ...
H2O2-preconditioned human adipose-derived stem cells (HC016) increase theirresistance to oxidative stress byoverexpressing Nrf2 and bioenergetic adaptation
(Biomed Central, 2020-08-03)
BackgroundMesenchymal stem cells, including those derived from human adipose tissue (hASCs), are currently being widely investigated for cell therapy. However, when transplanted at the site of injury, the survival and ...
Hydrogen Peroxide-Preconditioned Human Adipose-Derived Stem Cells Enhance the Recovery of Oligodendrocyte-Like Cells after Oxidative Stress-Induced Damage
(MDPI, 2020-12-14)
Oxidative stress associated with neuroinflammation is a key process involved in the pathophysiology of neurodegenerative diseases, and therefore, has been proposed as a crucial target for new therapies. Recently, the ...
Elucidation of the molecular and bionergetic mechanisms underlying the resistance to oxidatives stress and the pro-recovery effect of H2O2- preconditioned adipose-derived stem cells
(2020-06-11)
In the field of regenerative medicine, it has been pointed out the relevance of human adipose derived stem cells (hASCs) for cell therapy. They can be easily obtained, have low immunogenicity, and secrete soluble factors ...
Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation?
(Wiley, 2019-04)
Background: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) measured the global prevalence of symptoms of asthma in children. We undertook comprehensive analyses addressing risk factors ...