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Variations of telencephalic development that paved the way for neocortical evolution
(Elsevier, 2020-11)
Charles Darwin stated, "community in embryonic structure reveals community of descent". Thus, to understand how the neocortex emerged during mammalian evolution we need to understand the evolution of the development of the ...
External surface anatomy of the postfolding human embryo: Computer-aided, three-dimensional reconstruction of printable digital specimens
(2021-12)
Opportunities for clinicians, researchers, and medical students to become acquainted with the three-dimensional (3D) anatomy of the human embryo have historically been limited. This work was aimed at creating a collection ...
A deep intronic splice variant advises reexamination of presumably dominant SPG7 Cases
(Wiley, 2020-01)
Objective To identify causative mutations in a patient affected by ataxia and spastic paraplegia. Methods Whole-exome sequencing (WES) and whole-genome sequencing (WGS) were performed using patient's DNA sample. RT-PCR and ...
Embedding interactive, three-dimensional content in portable document format to deliver gross anatomy information and knowledge
(Wiley, 2021-09)
The Portable Document Format (PDF) is likely the most widely used digital file format for scholarly and scientific electronic publishing. Since format specification version 1.6, three-dimensional (3D) models in Universal ...
Local translation in nervous system pathologies
(Frontiers Media, 2021-06-29)
[EN] Dendrites and axons can extend dozens to hundreds of centimeters away from the
cell body so that a single neuron can sense and respond to thousands of stimuli.
Thus, for an accurate function of dendrites and axons ...
Mens sana in corpore sano: lifestyle changes modify astrocytes to contain Alzheimer’s disease
(Wolters Kluwer, 2021-08)
Astrocyte dystrophy in ageing brain parallels impaired synaptic plasticity
(2021-03)
Little is known about age-dependent changes in structure and function of astrocytes and of the impact of these on the cognitive decline in the senescent brain. The prevalent view on the age-dependent increase in reactive ...
Secondary Impacts of COVID-19 Pandemic in Fatigue, Self-Compassion, Physical and Mental Health of People with Multiple Sclerosis and Caregivers: The Teruel Study
(MDPI, 2021-09-18)
The secondary impacts of the COVID-19 pandemic are distress triggers and risk factors for mental health. Conversely, self-compassion skills and compassionate thoughts/behaviors towards suffering may contribute to their ...
Lifestyle-dependent microglial plasticity: training the brain guardians
(BMC, 2021-08-03)
Lifestyle is one of the most powerful instruments shaping mankind; the lifestyle includes many aspects of interactions with the environment, from nourishment and education to physical activity and quality of sleep. All ...
Characterization of blood markers and their implication in human aging.
(2020-01-13)
Aging is a universal, complex and heterogeneous process. In the last decades, an overall improvement in the quality of life and consequent increase in life expectancy has been achieved. In contrast, the disability-free ...