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Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia
(Nature Research, 2022-01-10)
[EN] Previous research suggests an association of loneliness and social isolation (LNL-ISO) with schizophrenia. Here, we demonstrate a LNL-ISO polygenic score contribution to schizophrenia risk in an independent case-control ...
Cognition in Recent Suicide Attempts: Altered Executive Function
(Frontiers Media, 2021-07-22)
Background: Neuropsychological alterations can lead to inaccurate perception, interpretation, and response to environmental information, which could be a risk factor for suicide.
Methods: Ninety-six subjects were recruited ...
COVID-19 pandemic effects on health worker’s mental health: Systematic review and meta-analysis
(Cambridge University Press, 2022)
[EN] Background Healthcare workers (HCWs) exposed to coronavirus 19 (COVID-19) are at high risk of developing mental health concerns across several domains. The aim of this study is to determine the updated, global frequency ...
Overview of lithium's use: a nationwide survey
(Springer, 2021-03-09)
BACKGROUND: Lithium is considered the gold standard treatment for bipolar disorder (BD). Current clinical guidelines and scientific evidence support its use as a first-line treatment in BD. However, over the last two ...
Gene Regulatory Network in Schwann cell Disorders
(2020-06-24)
Cancer cells can develop a strong addiction to discrete molecular regulators, which control the aberranttranscription programs that drive and maintain the cancer phenotype. Here, we report the identificationof the RNA-binding ...
Impact of the transient receptor potential vanilloid 1 deletion on the endocannabinoid system in the mouse dentate gyrus
(2020-06-19)
En este trabajo de tesis doctoral se ha analizado como la delección genética de un receptor afecta al resto del sistema con el que interactúa. Más concretamente, se ha establecido cuáles han sido los cambios en el sistema ...
A qualitative research of adolescents with behavioral problems about their experience in a dialectical behavior therapy skills training group
(BMC, 2020-05-19)
BACKGROUND: Several quantitative studies support the effectiveness of the Dialectical Behavior Therapy (DBT) psychosocial skills training group component for adolescents with impulse-control disorder and/or emotional ...
Proportion and predictors of remission and recovery in first-episode psychosis: Systematic review and meta-analysis
(Cambridge University Press, 2021-11)
[EN] Background To determine the proportion of patients in symptomatic remission and recovery following a first-episode of psychosis (FEP). Methods A multistep literature search using the Web of Science database, Cochrane ...
Gut microbiota, innate immune pathways, and inflammatory control mechanisms in patients with major depressive disorder
(Springer Nature, 2021-12-21)
[EN] Although alterations in the gut microbiota have been linked to the pathophysiology of major depressive disorder (MDD), including through effects on the immune response, our understanding is deficient about the straight ...
Cannabis use and nonuse in patients with first-episode psychosis: A systematic review and meta-analysis of studies comparing neurocognitive functioning
(Association of European Psychiatrists, 2020-01-31)
BACKGROUND.: The implications of cannabis use in the onset of early psychosis and the severity of psychotic symptoms have resulted in a proliferation of studies on this issue. However, few have examined the effects of ...