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Now showing items 14681-14690 of 15147
Metholological approach for landslide analysis in a regional scale. Data collection, susceptibility models and precipitation thresholds.Application in Gipuzkoa province (Basque Country)
(2018-12-20)
Lurraldearen zonazioa lur labainketak jasotzeko aukeren arabera, suszeptibilitate mapen bitartez hain zuzen ere, hauek eragindako kalteak arindu eta mehatxua eta arrisku maila ebaluatu ahal izateko oinarrizko pausoa da. ...
New genetic markers for treatment personalization in pediatric acute lymphoblastic leukemia
(2013-05-28)
La Leucemia Linfoblástica Aguda (LLA) es el cáncer pediátrico más común. Es un desorden de las células linfoblásticas, que son las precursoras de las células linfáticas, y se caracteriza por la acumulación en médula ósea ...
Variants in the 14q32 miRNA cluster are associated with osteosarcoma risk in the Spanish population
(Nature Publishing, 2018-10-18)
Association studies in osteosarcoma risk found significant results in intergenic regions, suggesting that regions which do not codify for proteins could play an important role. The deregulation of microRNAs (miRNAs) has ...
Desinformación y credibilidad en el ecosistema digital: actas del XII Congreso Internacional de Ciberperiodismo
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2021)
Mir-pharmacogenetics in childhood acute lymphoblastic leukemia treatment
(2018-09-20)
La leucemia Linfoblástica Aguda (LLA) es la neoplasia más frecuente en la población pediátrica. La supervivencia global de la LLA supera hoy día el 80%, en parte gracias a la intensificación del tratamiento. Sin embargo, ...
Conjugative Coupling Proteins and the Role of Their Domains in Conjugation, Secondary Structure and in vivo Subcellular Location
(Frontiers Media, 2020-08-11)
Type IV Coupling Proteins (T4CPs) are essential elements in many type IV secretion systems (T4SSs). The members of this family display sequence, length, and domain architecture heterogeneity, being the conserved ...
Extension and improvement of synchronous linear generator based point absorber operation in high wave excitation scenarios
(Elsevier, 2021-11-01)
[EN]The exploitation of marine wave energy resource has led to the design of numerous Wave Energy Converter (WEC) configurations. The power absorption of a WEC is tightly related to its physical properties and the ...
Truncation-Driven Lateral Association of α-Synuclein Hinders Amyloid Clearance by the Hsp70-Based Disaggregase
(MDPI, 2021-11-30)
The aggregation of α-synuclein is the hallmark of a collective of neurodegenerative disorders known as synucleinopathies. The tendency to aggregate of this protein, the toxicity of its aggregation intermediates and the ...
Prognostic and therapeutic value of somatic mutations in diffuse large B-cell lymphoma: A systematic review
(Elsevier, 2021-09)
Diffuse large B-cell lymphoma (DLBCL), the most common type of Non-Hodgkin lymphoma (NHL), is a highly heterogeneous and aggressive disease. Regardless of this heterogeneity, all patients receive the same first-line therapy, ...
Hypersensitivity to Pegylated E.coli asparaginase as first-line treatment in contemporary paediatric acute lymphoblastic leukaemia protocols: a meta-analysis of the Ponte di Legno Toxicity working group
(Elsevier, 2022-02)
[EN] BACKGROUND: Hypersensitivity reactions to asparaginase challenge its use and occur frequently (30-75%) after native Escherichia Coli (E.coli) asparaginase. Comparison of incidence of allergic reactions to pegylated ...