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Now showing items 14721-14730 of 15031
Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia
(Springer Nature, 2020-03)
Identification of genomic and epigenomic determinants of drug resistance provides important insights for improving cancer treatment. Using agnostic genome-wide interrogation of mRNA and miRNA expression, DNA methylation, ...
Automated procedure to detect subtle motor alterations in the balance beam test in a mouse model of early Parkinson’s disease
(Nature, 2024)
Parkinson’s disease (PD) is the most common motor neurodegenerative disorder, characterised by aggregated α-synuclein (α-syn) constituting Lewy bodies. We aimed to investigate temporal changes in motor impairments in a PD ...
Multicoverage Study of Femtosecond Laser-Induced Desorption of CO from Pd(111)
(ACS, 2024-02)
We study the strong coverage dependence of the femtosecond laser-induced desorption of CO from Pd(111) using molecular dynamics simulations that consistently include the effect of the laser-induced hot electrons on both ...
Synthesis of Waterborne Anticorrosive Coatings Based on The Incorporation of Phosphate Groups to Polyurethane-Acrylate Hybrids
(Wiley, 2023-08)
In this work, solvent-free waterborne polyurethane-poly(meth)acrylate hybrid dispersions that can be used to formulate anticorrosive paints are synthesized. To achieve the anticorrosive protection, a phosphate containing ...
Experimental and Numerical Characterization of Mechanical Behavior and Wear Pattern of Vitreous Bonding Grinding Wheels
(2023-12-15)
Introducción al Rectificado y el Papel de las Muelas Abrasivas: El rectificado es esencial en la manufactura para obtener tolerancias precisas y componentes duraderos. Los avances recientes se centran en mejorar la tecnología ...
Metholological approach for landslide analysis in a regional scale. Data collection, susceptibility models and precipitation thresholds.Application in Gipuzkoa province (Basque Country)
(2018-12-20)
Lurraldearen zonazioa lur labainketak jasotzeko aukeren arabera, suszeptibilitate mapen bitartez hain zuzen ere, hauek eragindako kalteak arindu eta mehatxua eta arrisku maila ebaluatu ahal izateko oinarrizko pausoa da. ...
New genetic markers for treatment personalization in pediatric acute lymphoblastic leukemia
(2013-05-28)
La Leucemia Linfoblástica Aguda (LLA) es el cáncer pediátrico más común. Es un desorden de las células linfoblásticas, que son las precursoras de las células linfáticas, y se caracteriza por la acumulación en médula ósea ...
Variants in the 14q32 miRNA cluster are associated with osteosarcoma risk in the Spanish population
(Nature Publishing, 2018-10-18)
Association studies in osteosarcoma risk found significant results in intergenic regions, suggesting that regions which do not codify for proteins could play an important role. The deregulation of microRNAs (miRNAs) has ...
Desinformación y credibilidad en el ecosistema digital: actas del XII Congreso Internacional de Ciberperiodismo
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2021)
Mir-pharmacogenetics in childhood acute lymphoblastic leukemia treatment
(2018-09-20)
La leucemia Linfoblástica Aguda (LLA) es la neoplasia más frecuente en la población pediátrica. La supervivencia global de la LLA supera hoy día el 80%, en parte gracias a la intensificación del tratamiento. Sin embargo, ...