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Now showing items 14951-14960 of 15051
Determining the binding kinetics and signalling effects of CB1 and CB2 receptor ligands; a closer look at residence time and functional selectivity
(2022-05-30)
The CB1 and CB2 receptors are the main GPCRs of the endocannabinoid system, and regulate many important physiological processed as pain, inflammation, or behaviour. Increasing interest exist to develop new drugs targeting ...
Exploring Martian and Lunar geochemistry through the study of meteorites, analogs, laboratory simulations, and analysis of mission data
(2023-05-17)
This PhD Thesis is focused on the geochemical study of the Moon and Mars in order to provide science support for current and future space missions. Throughout this thesis a bibliographic review of all the past and current ...
Exploring HIV-1 lipid-interacting partners by chemical-based approaches.
(2022-06-07)
Esta tesis doctoral se ha centrado en el empleo de diferentes herramientas químicas desarrolladas para el estudio de interacciones lípido-proteína y proteína-proteína en el contexto del Virus de la Inmunodeficiencia Humana ...
Extended Enolates: Versatile Intermediates for Asymmetric C-H Functionalization via Noncovalent Catalysis
(Wiley, 2021)
Catalyst-controlled functionalization of unmodified carbonyl compounds is a relevant operation in organic synthesis, especially when high levels of site- and stereo-selectivity can be attained. This objective is now within ...
Capacity and Impedance Estimation by Analysing and Modeling in Real Time Incremental Capacity Curves
(MDPI, 2020-09-16)
The estimation of lithium ion capacity fade and impedance rise on real application is always
a challenging work due to the associated complexity. This work envisages the study of the battery
charging profile indicators ...
Application Dependent End-of-Life Threshold Definition Methodology for Batteries in Electric Vehicles
(MDPI, 2021-02-11)
The end-of-life event of the battery system of an electric vehicle is defined by a fixed end-of-life threshold value. However, this kind of end-of-life threshold does not capture the application and battery characteristics ...
Brønsted Base Catalyzed One-Pot Synthesis od Stereodefined Six-Member Carbocycles Featuring Transient Trienolates and a Key Intramolecular 1,6-Addition
(Wiley-VCH, 2019-07-31)
Acatalyst-driven one-pot reaction sequence is
developed for the enantio- and diastereoselective synthesis of
tetrasubstituted cyclohexenes from simple unsaturated ketones
or thioesters.The method involves atertiary ...
Autonomous infrastructure management for multi-cloud kubernetes clusters
(2024-05-10)
This project develops an Autonomous Infrastructure Management for Multi-Cloud Kubernetes Clusters, where the focus lies in harnessing Kubernetes' APIs to construct and govern an autonomous cluster infrastructure in a ...
Detecting Areas of Improvement in Secondary Education: Listening to Management Teams and Teachers
(Universidad Pedagógica Nacional (Colombia), 2024-04-01)
The general aim of this research study is to detect needs and possible areas of improvement
in the Basque education system. To this end, this paper describes and compares
the discourses of different informants, using a ...
QoX enhancement in campus Wi-Fi networks: a machine learning approach
(2024-05-10)
El desarrollo de nuevas tecnologías, junto con las crecientes exigencias de los usuarios de éstas, ha puesto en el punto de mira la gestión de la calidad de servicio (QoS) de las redes de telecomunicaciones. Por este motivo, ...