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Regulation of Nociceptive Plasticity Threshold and DARPP-32 Phosphorylation in Spinal Dorsal Horn Neurons by Convergent Dopamine and Glutamate Inputs
(Public Library Science, 2016-09-09)
Dopamine can influence NMDA receptor function and regulate glutamate-triggered long-term changes in synaptic strength in several regions of the CNS. In spinal cord, regulation of the threshold of synaptic plasticity may ...
Influence of chain topology (cyclic versus linear) on the nucleation and isothermal crystallization of poly(L-lactide) and poly(D-lactide)
(American Chemical Society, 2018-02-20)
In this paper, ring closure click chemistry methods have been used to produce cyclic c-PLLA and c-PDLA of a number average molecular weight close to 10 kg/mol. The effects of stereochemistry of the polymer chains and their ...
Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum
(MDPI, 2019-04-14)
The most common cystic fibrosis-causing mutation (F508del, present in ~85% of CF patients) leads to CFTR misfolding, which is recognized by the endoplasmic reticulum (ER) quality control (ERQC), resulting in ER retention ...
Crystallization of isodimorphic aliphatic random copolyesters: pseudo-eutectic behavior and double-crystalline materials
(Elservier, 2018-02-28)
Isodimorphic random copolyesters are intriguing polymeric materials that can crystallize in their entire composition range, despite the random distribution of comonomer units along their chains. This behavior stems from ...
Morphological processing in the brain: The good (inflection), the bad (derivation) and the ugly (compounding)
(Cortex, 2019)
There is considerable behavioral evidence that morphologically complex words such as ‘tax-able’ and ‘kiss-es’ are processed and represented combinatorially. In other words, they are decomposed into their constituents ‘tax’ ...
Association of Birth Order with Cardiovascular Disease Risk Factors in Young Adulthood: A Study of One Million Swedish Men
(Public Library of Science, 2013-05-16)
Background: Birth order has been suggested to be linked to several cardiovascular disease (CVD) risk factors, but the evidence is still inconsistent. We aim to determine the associations of birth order with body mass index ...
Mean Stress Effect on the Axial Fatigue Strength of DIN 34CrNiMo6 Quenched and Tempered Steel
(MDPI, 2018-04)
The present study consists of a theoretical and experimental investigation of the effect of axial mean stresses on the high cycle fatigue behaviour of DIN 34CrNiMo6 high strength steel in quenched and tempered conditions. ...
Secure Protocol and IP Core for Configuration of Networking Hardware IPs in the Smart Grid
(MDPI, 2018-03)
Nowadays, the incorporation and constant evolution of communication networks in the electricity sector have given rise to the so-called Smart Grid, which is why it is necessary to have devices that are capable of managing ...
Putative Role of Respiratory Muscle Training to Improve Endurance Performance in Hypoxia: A Review
(Frontiers Media, 2019-01-15)
Respiratory/inspiratory muscle training (RMT/IMT) has been proposed to improve the endurance performance of athletes in normoxia. In recent years, due to the increased use of hypoxic training method among athletes, the RMT ...
Experimental Validation of the Kinematic Design of 3PRS Compliant Parallel Mechanisms
(Elsevier, 2016-11)
In this paper, a procedure for the kinematic design of a 3-PRS compliant parallel manipulator of 3 degrees of freedom is proposed. First, under the assumption of small displacements, the solid body kinematics of the 3-PRS ...