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Acute L-DOPA administration reverses changes in firing pattern and low frequency oscillatory activity in the entopeduncular nucleus from long term L-DOPA treated 6-OHDA-lesioned rats
(Elsevier, 2019-12)
The pathophysiology of Parkinson's disease (PD) and L-DOPA-induced dyskinesia (LID) is associated with aberrant neuronal activity and abnormal high levels of oscillatory activity and synchronization in several basal ganglia ...
RNA-Seq analysis of ileocecal valve and peripheral blood from Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis revealed dysregulation of the CXCL8/IL8 signaling pathway
(Nature Publishing Group, 2019-10-16)
Paratuberculosis is chronic granulomatous enteritis of ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). Whole RNA-sequencing (RNA-Seq) is a promising source of novel biomarkers for early MAP infection ...
Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial
(MDPI, 2019-10-01)
Age-related strength and muscle mass loss is further increased after acute periods of inactivity. To avoid this, resistance training has been proposed as an effective countermeasure, but the additional effect of a protein ...
Electrospinning of Fish Gelatin Solution Containing Citric Acid: An Environmentally Friendly Approach to Prepare Crosslinked Gelatin Fibers
(MDPI, 2019-09-01)
The majority of the crosslinking approaches employed to confer water resistance properties to electrospun gelatin mats are based on the use of potential cytotoxic agents, turning out to be not suitable for biomedical ...
Prediction Methods and Experimental Techniques for Chatter Avoidance in Turning Systems: A Review
(MDPI, 2019-11)
The general trend towards lightweight components and stronger but difficult to machine materials leads to a higher probability of vibrations in machining systems. Amongst them, chatter vibrations are an old enemy for ...
Evaluation of two virtual cursors for assisting web access to people with motor impairments
(Elsevier, 2019-08-02)
People with motor impairments (MI) may face accessibility barriers when using computers due to their health conditions and therefore need to use alternative devices to a standard mouse for pointing and clicking in graphical ...
Changes in Surface Tension of Aqueous Humor in Anterior Segment Ocular Pathologies
(MDPI, 2016-09)
The aim of this study was to identify and determine differences in surface tension (ST) of aqueous humor (AH) in patients with cataract, glaucoma and Fuchs endothelial dystrophy (FED). Two hundred and two samples of AH ...
Solitons and black hole in shift symmetric scalar-tensor gravity with cosmological constant
(Springer, 2018-06-14)
We demonstrate the existence of static, spherically symmetric globally regular, i.e. solitonic solutions of a shift-symmetric scalar-tensor gravity model with negative cosmological constant. The norm of the Noether current ...
Recent Advances in Homogeneous Metal-Catalyzed Aerobic C–H Oxidation of Benzylic Compounds
(MDPI, 2018-12-08)
Csp(3)-H oxidation of benzylic methylene compounds is an established strategy for the synthesis of aromatic ketones, esters, and amides. The need for more sustainable oxidizers has encouraged researchers to explore the use ...
The Crossroad of Ion Channels and Calmodulin in Disease
(MDPI, 2019-01-02)
Calmodulin (CaM) is the principal Ca2+ sensor in eukaryotic cells, orchestrating the activity of hundreds of proteins. Disease causing mutations at any of the three genes that encode identical CaM proteins lead to major ...