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DNA methylation epigenotypes in breast cancer molecular subtypes
(BioMed Central, 2010-09-29)
Introduction: Identification of gene expression-based breast cancer subtypes is considered a critical means of prognostication. Genetic mutations along with epigenetic alterations contribute to gene-expression changes ...
PR-LncRNA Signature Regulates Glioma Cell Activity Through Expression of SOX Factors
(Nature Publishing Group, 2018-08-24)
Long non-coding RNAs (LncRNAs) have emerged as a relevant class of genome regulators involved in a broad range of biological processes and with important roles in tumor initiation and malignant progression. We have previously ...
Blood miRNA expression pattern is a possible risk marker for natalizumab-associated progressive multifocal leukoencephalopathy in multiple sclerosis patients
(Sage, 2014-05-22)
Background: Natalizumab has shown its efficacy in reducing multiple sclerosis (MS) relapses and progression of disability; however, it has been associated with an increased risk of developing progressive multifocal ...
Transcription of ribogenesis genes in fish gonads: Applications in the identification of stages of oogenesis and in environmental monitoring of intersex condition
(Elsevier, 2017-06-13)
One of the best described effects of environmental xenoestrogens in fish is the generation of intersex gonads in males. Considering 5S rRNA a marker of the presence of oocytes, a 5S/18S rRNA index was calculated in 296 ...
Capnography: A support tool for the detection of return of spontaneous circulation in out-of-hospital cardiac arrest
(Elsevier, 2019-09)
Background
Automated detection of return of spontaneous circulation (ROSC) is still an unsolved problem
during cardiac arrest. Current guidelines recommend the use of capnography, but most
automatic methods are based ...
A feedforward controller for tuning laser cladding melt pool geometry in real time
(Springer, 2016-07-12)
In this paper, a feedforward proportional-integral (PI) controller is developed to effectively control and tune the laser cladding melt pool geometry in real time. Width setpoint is included in the computer numerically ...
Influence of the regulation framework on the feasibility of a Stirling engine-based residential micro-CHP installation
(Elsevier, 2015-04-07)
In this paper an economic analysis of a 1 kWe Stirling engine-based micro-CHP (combined heat and power) residential plant is developed, approaching the case of a Spanish detached house sited in a cold climatic zone. The ...
An archaeometrical approach to the majolica pottery from Alcazar de Najera archaeological site
(Springer, 2019-05-22)
The city of Nájera, located in the north of the Iberian Peninsula, hosts an alcazar of Arab origin, which became the residence of the king of Pamplona-Nájera and later of the duke and duchess of Nájera. From this last ...
Relevance for decision making of spatially explicit, participatory scenarios for ecosystem services in an area of a high current demand
(Elsevier, 2015-07-23)
Participatory ecosystem services scenarios can be used to inform decision making on the sustainable or wise use of biodiversity and Ecosystem Services (ES). To establish the plausibility and coherency of the recently ...
Catalysts of Ni/α-Al2O3 and Ni/La2O3-αAl2O3 for hydrogen production by steam reforming of bio-oil aqueous fraction
(Elsevier, 2012-12-04)
This paper reports on the steam reforming, in continuous regime, of the aqueous fraction of bio-oil obtained by flash pyrolysis of lignocellulosic biomass (sawdust). The reaction system is provided with two steps in series: ...