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Mostrando ítems 9191-9197 de 9197
Cholesterol Constrains the Antigenic Configuration of the Membrane-Proximal Neutralizing HIV-1 Epitope
(ACS, 2020-06-25)
The envelope glycoprotein (Env) enables HIV-1 cell entry through fusion of host-cell and viral membranes induced by the transmembrane subunit gp41. Antibodies targeting the C-terminal sequence of the membrane-proximal ...
Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface
(Springer Nature, 2016-12-01)
The mechanism by which the HIV-1 MPER epitope is recognized by the potent neutralizing antibody 10E8 at membrane interfaces remains poorly understood. To solve this problem, we have optimized a 10E8 peptide epitope and ...
Confocal microscopy of giant vesicles supports the absence of HIV-1 neutralizing 2F5 antibody reactivity to plasma membrane phospholipids
(Elsevier, 2010-03-17)
The broadly neutralizing anti-HIV-1 2F5 monoclonal antibody recognizes a gp41 epitope proximal to the viral membrane. Potential phospholipid autoreactivity at cell surfaces has raised concerns about the use of this antibody ...
Procedure to Identify the Technological and Constructive Values in Historical Lighthouses: Application to the Lighthouses of Spain
(ASCE, 2020-06-22)
The paper analyzes the heritage values of the lighthouses related with science, technology and the construction in the age they were built and launched along the history. The implementation of a lighthouse requires the ...
Pre-renaissance Manor Houses in the Basque Country (Spain): Analysis of the Loyola Tower Palace
(Springer Nature, 2020-07-31)
At the end of the fifteenth century, there was a shift from a defensive Tower House residential model to a type of palatial-style residential model. The Loyola Tower Palace, located in the Basque Country (Spain), is an ...
The Ekihouse: An energy self-sufficient house based on passive design strategies
(Elsevier, 2014-11)
EKIHOUSE is an industrialized solar house prototype designed and developed by the University of the Basque Country for the SOLAR DECATHLON EUROPE 2012 competition that took place in Madrid (Spain). The building design ...
Retrofit strategies towards Net Zero Energy Educational Buildings: a case study at the University of the Basque Country.
(Elsevier, 2017-03-31)
Educational buildings in Europe account for around 20% of the entire non-residential floor space where good indoor comfort and air quality are essential for correct educational development. Directive 2010/31/UE upholds ...