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Triacylglycerol mimetics regulate membrane interactions of glycogen branching enzyme: implications for therapy
(Elsevier, 2017-06-19)
Adult polyglucosan body disease (APBD) is a neurological disorder characterized by adult-onset neurogenic bladder, spasticity, weakness, and sensory loss. The disease is caused by aberrant glycogen branching enzyme (GBE) ...
Multiple-Criteria Decision-Making Tool for Local Governments to Evaluate the Global and Local Sustainability of Transportation Systems in Urban Areas: Case Study
(ASCE, 2017-10-24)
Efficient management of urban transportation systems is a challenge for any local government that wishes to improve public wellbeing and comfort. With that end in mind, this paper proposes a tool for decision making and ...
Speed deficiency in shipbuilding contracts from the point of view of an efficient managing of the main engine
(University of Santander, 2010)
This article is related to the shipbuilding contracts and its purpose is to provide amethod of calculation of the economical damages sustained by a purchaser due tothe speed deficiency of the vessel delivered by the shipyard. ...
Combined Fluorescent-Chromogenic In Situ Hybridization for Identification and Laser Microdissection of Interphase Chromosomes
(Public Library of Science, 2013)
Chromosome territories constitute the most conspicuous feature of nuclear architecture, and they exhibit non-random distribution patterns in the interphase nucleus. We observed that in cell nuclei from humans with Down ...
Stability of CuZnOAl2O3/HZSM-5 and CuFe2O4/HZSM-5 catalysts in dimethyl ether steam reforming operating in reaction-regeneration cycles
(Elsevier, 2014-05-21)
The study focuses on the regenerability of bifunctional catalysts prepared with different metallic functions (CuZnOAl2O3 and CuFe2O4 spinel) and HZSM-5 zeolite (SiO2/Al2O3 = 30) as the acid function. These catalysts have ...
Steam reforming of raw bio-oil in a fluidized bed reactor with prior separation of pyrolytic lignin
(ACS, 2013-11-11)
The effect operating conditions (temperature, steam/carbon molar ratio and space-velocity) have on the steam reforming of raw bio-oil has been studied in a two-step reaction unit. In the first step (operated at 500 ºC), a ...
A systematic review and meta-analysis of MTHFR polymorphisms in methotrexate toxicity prediction in pediatric acute lymphoblastic leukemia
(Springer, 2013-10-23)
Methotrexate (MTX) is an important component of therapy used to treat childhood acute lymphoblastic leukemia (ALL). Two single-nucleotide polymorphisms (SNPs) in the methylenetetrahydrofolate reductase (MTHFR) gene, C677T ...
High Mitochondrial DNA Stability in B-Cell Chronic Lymphocytic Leukemia
(Public Library Science, 2009-11-18)
Background: Chronic Lymphocytic Leukemia (CLL) leads to progressive accumulation of lymphocytes in the blood, bone marrow, and lymphatic tissues. Previous findings have suggested that the mtDNA could play an important role ...
Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population
(Public Library Science, 2017-05-08)
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the long noncoding RNA (lncRNA) known as ANRIL (or CDKN2B-AS), was associated with childhood acute lymphoblastic leukemia (ALL) ...
Synthesis and characterization of epoxy polymers containing azobenzene groups that exhibit optical birefringence
(2007-12-03)
A push–pull azo dye (DO3) was used as photosensitive substance to satisfactorily synthesize new epoxy polymers containing azo groups covalently linked. Three different amines BA, TA and MXDA were used as hardeners. Materials ...