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Now showing items 20361-20370 of 20584
Progress in (Thio)urea‐ and Squaramide‐Based Brønsted Base Catalysts with Multiple H‐Bond Donors
(Wiley, 2023-02)
Nowadays chiral (thio)urea- and squaramide-based Brønsted base catalysts are widely applied to enantioselective carbon-carbon and carbon-heteroatom bond forming reactions. In recent years, variations of these catalysts ...
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits
(2015-05-27)
For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular,
height and body mass index (BMI, calculated as kg/m2) have been under intensive genetic research.
However, ...
Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study
(Elsevier, 2016-07-13)
Background: Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking. Objectives: We analyzed the ...
Characterization of the Antitumor Potential of Extracts of Cannabis sativa Strains with High CBD Content in Human Neuroblastoma
(MDPI, 2023-02-14)
Cannabis has been used for decades as a palliative therapy in the treatment of cancer. This is because of its beneficial effects on the pain and nausea that patients can experience as a result of chemo/radiotherapy. ...
Enantioselective Construction of Tetrasubstituted Stereogenic Carbons through Brønsted Base Catalyzed Michael Reactions: α´-Hydroxy Enones as Key Enoate Equivalent
(ACS, 2014-11-25)
Catalytic and asymmetric Michael reactions constitute very powerful tools for the construction of new C–C bonds in synthesis, but most of the reports claiming high selectivity are limited to some specific combinations of ...
Asymmetric Synthesis of Adjacent Tri- and Tetrasubstituted Carbon Stereocenters: Organocatalytic Aldol Reaction of an Hydantoin Surrogate with Azaarene 2-Carbaldehydes
(Wiley-VCH, 2019-07-18)
A bifunctional amine/squaramide catalyst promoted direct aldol addition of an hydantoin surrogate to pyridine 2-carbaldehyde N-oxides to afford adducts bearing two vicinal tertiary/quaternary carbons in high diastereo- and ...
Enantioselective Addition of Alkynyl Ketones to Nitroolefins Assisted by Bronsted Base/H-Bonding Catalysis
(Wiley, 2019-03-21)
Various sets of enolizable alkynyl ketones (including methyl ynones with α-aryl, α-alkenyl, and α-alkoxy groups) were able to react smoothly with nitroolefins with the assistance of bifunctional Brønsted base/H-bond catalysts ...
Estresa, migraina eta hirugarren belaunaldiko terapiak
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2024-05-27)
Gaur egun, gero eta sarriagoak dira inolako etiologia zehatz gabeko gaixotasun eta nahasmenduak. Eguneroko estresa min kronikoa garatzeko arrisku faktorea da. Migraina min kroniko posible horietako bat da. Badakigu estres ...
α-Hydroxy Ketones as Masked Ester Donors in Brønsted Base-Catalyzed Conjugate Additions to Nitroalkenes
(ChemPubSoc Europe, 2018-02-15)
Crystallization-induced self-assembly of poly(ethylene glycol) side chains in dithiol–yne-based comb polymers: side chain spacing and molecular weight effects
(ACS, 2024-05)
The chain architecture and topology of macromolecules impact their physical properties and final performance, including their crystallization process. In this work, comb polymers constituted by poly(ethylene glycol), PEG, ...