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Desarrollo de nanopartículas sólidas lipídicas como sistemas de administración de ADN para terapia génica
(2013-10-24)
[EN] This work includes the development, characterization and optimization of a gene delivery system based on solid lipid nanoparticles (SLNs) . Formulations were characterized in terms of particle size , surface charge ...
The role of the cationic and helper lipids on niosomes for gene delivery applications: transfection of retina and brain as a main goal.
(2016-09-23)
Currently, gene delivery has become a tangible option for the treatment of several diseases. However, there are few available options in the market, where viral vectors are the preferred option due to their high transduction ...
Application of green nanoscience to olive polyphenols: Formulation design and biological evaluation of oleuropein-loaded nanstructured lipid carriers
(2020-11-06)
Esta tesis doctoral nace del interés de BIOSASUN en el desarrollo de formulaciones novedosas como solución a las limitaciones que presentan los polifenoles del olivo. Ello, unido a la especialidad del Grupo Nanobiocel en ...
Plasma Rich in Growth Factors technology: characterization, regulatory framework, current trends and perspectives
(2020-12-18)
La tecnología de plasma rico en factores de crecimiento, PRGF (por sus siglas en inglés, Plasma Rich in Growth Factors) es una terapia biológica autóloga que utiliza los propios componentes de la sangre del paciente como ...
Tailored gelatin-based three-dimensional sysems for bone tissue engineering.
(2019-12-17)
The current Doctoral Thesis is focused on the development of three-dimensional systems for bone tissue engineering purposes. Gelatin was chosen as the main material to manufacture scaffolds capable for serving as both ...
Bioanthropology of obesity in a population of the Autonomus Community of the Basque Country
(2017-09-18)
Obesity has become a major health concern worldwide due to its increasing prevalence and its detrimental health impact. The overarching aim of the present thesis was to study the aetiology of obesity from anthropological, ...
Changes in lipids and formation of derived compounds during fish cooking and in vitro gastrointestinal digestion of edible oils, model systems and processed fish meat
(2017-03-07)
En la presente tesis doctoral se plantearon cuatro objetivos principales. En el primer objetivo, se estudiaron los cambios provocados por el proceso de cocinado en los lípidos y/o perfil volátil del pescado mediante ...
Antibiotic-loaded nanstructured lipid carriers (NLCs) for multiresistant respiratory tract and wound infections.
(2020-12-10)
La resistencia a los antibióticos (AMR) es un problema grave que debe abordarse lo antes posible. La colistina y la amikacina representan unos de los pocos antibióticos eficaces contra las infecciones de las bacterias ...
Biofunctionalization of alginate microcapsules: advances in cell-based drug delivery systems
(2015-09-16)
En la tesis titulada Biofunctionalization of alginate microcapsules: advances in cell-based drug delivery systems se han realizado tres trajajos experimentales basados en microcápsulas de alginato modificadas con diferentes ...
Evaluación clínica y análisis coste-efectividad del envío de mensajes motivacionales como herramienta adyuvante para dejar de fumar.
(2020-11-27)
El tabaquismo constituye la primera causa de morbi-mortalidad evitable a nivel mundial. Es uno de los mayores problemas de salud pública al que se ha tenido que enfrentar lahumanidad, matando hasta la mitad de sus consumidores. ...