BackSearch
Now showing items 36931-36940 of 40080
Investigación evaluativa-apreciativa de los programas de justicia restaurativa en el ámbito penitenciario en Euskadi
Varona Martínez, Gema 
; Igartua Laraudogoitia, Idoia ; ; Orbegozo Oronoz, Izaskun (Laboratorio de Teoría y Práctica de Justicia Restaurativa, 2024-01-30)
; Igartua Laraudogoitia, Idoia ; ; Orbegozo Oronoz, Izaskun (Laboratorio de Teoría y Práctica de Justicia Restaurativa, 2024-01-30)
Esta investigación, de corte analítico y propositivo, se integra específicamente en el marco de las actividades del Laboratorio de Teoría y Práctica de Justicia Restaurativa (LTPJR) (IVAC/KREI), en cuyo equipo se integran ...
[n-/l- + herskari] taldeen bilakabide diakronikoa eta erronkarieraren lekukotasuna: irudia(k) fintzen
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2022)
In this article, we will analyze the opposition of occlusives posterior to n-/l- that have been debated in the history of Basque. Until recently, it was argued that the voiced stop is the oldest sound after the lateral and ...
Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: implications for antibody recognition mechanism and immunogen design
; ; Apellaniz Unzalu, Beatriz ; ; ; De la Arada Echevarría, Igor ; ; ; ; ; ; ; (Elsevier, 2014-01-15)
; ; ; De la Arada Echevarría, Igor ; ; ; ; ; ; ; (Elsevier, 2014-01-15)
The membrane-proximal external region (MPER) of gp41 harbors the epitope recognized by the broadly neutralizing anti-HIV 2F5 antibody, a research focus in HIV-1 vaccine development. In this work, we analyze the structure ...
The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region
Apellaniz Unzalu, Beatriz ; ; ; ; ; ; ; (Elsevier, 2015-03-18)
; ; ; ; ; ; ; (Elsevier, 2015-03-18)
The membrane-proximal external region (MPER) C-terminal segment and the transmembrane domain (TMD) of gp41 are involved in HIV-1 envelope glycoprotein-mediated fusion and modulation of immune responses during viral infection. ...
Distinct mechanisms of lipid bilayer perturbation induced by peptides derived from the membrane-proximal external region of HIV-1 gp41
Apellaniz Unzalu, Beatriz ; ; (ACS Publications, 2009-04-29)
; ; (ACS Publications, 2009-04-29)
The conserved, membrane-proximal external region (MPER) of the human immunodeficiency
virus type-1 envelope glycoprotein 41 subunit is required for fusogenic activity. It has been proposed that
MPER functions by disrupting ...
The three lives of viral fusion peptides
Apellaniz Unzalu, Beatriz ; ; ; (Elsevier, 2014-04)
; ; ; (Elsevier, 2014-04)
Fusion peptides comprise conserved hydrophobic domains absolutely required for the fusogenic activity of glycoproteins from divergent virus families. After 30 years of intensive research efforts, the structures and functions ...
Molecular Recognition of the Native HIV-1 MPER Revealed by STED Microscopy of Single Virions
; Chojnacki, Jakub; Rujas Díez, Edurne; ; ; Waithe, Dominic; Apellaniz Unzalu, Beatriz ; Sicard, Taylor; Julien, Jean Philippe; Eggeling, Christian; (Springer, 2019-01-08)
; Sicard, Taylor; Julien, Jean Philippe; Eggeling, Christian; (Springer, 2019-01-08)
Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure and accessibility, ...
GIBaren aurkako txertoaren bila
Torralba Iturbe, Johana ; ; Apellaniz Unzalu, Beatriz (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2017)
; ; Apellaniz Unzalu, Beatriz (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2017)
HIV is the causative agent of one of the most lethal pandemics in human history, AIDS. Although in recent years HAART therapy has considerably reduced death rate, new infections keep arising. Therefore, a preventive vaccine ...
Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
Torralba Iturbe, Johana ; De la Arada Echevarría, Igor ; ; ; ; ; ; ; ; ; ; Apellaniz Unzalu, Beatriz ; ; (Nature, 2022)
; De la Arada Echevarría, Igor ; ; ; ; ; ; ; ; ; ; Apellaniz Unzalu, Beatriz ; ; (Nature, 2022)
Antibodies against the carboxy-terminal section of the membrane-proximal external region (C-MPER) of the HIV-1 envelope glycoprotein (Env) are considered as nearly pan-neutralizing. Development of vaccines capable of ...