Search
Now showing items 1-10 of 19
S-adenosylmethionine: a metabolic driver in liver lipid metabolism and VLDL clearance
(2017-10-30)
La enfermedad del hígado graso no alcohólica, EHGNA o NAFLD, es la causa más frecuente en el mundo de enfermedad crónica hepática. Su desarrollo se ha asociado en algunos casos a un metabolismo errático de S-Adenosilmetionina ...
Understanding the role of miRNAs in the hallmarks of cancer using functional screens.
(2017-09-15)
En ésta tesis hemos estudiado la función de los miRNAs en las principales características o "hallmarks"del cáncer. Para ello hemos realizado cribados funcionales con una librería lentiviral para la sobreexpresiónde miRNAs ...
Long-term mortality in hospitalized patients with community-acquired pseumonia
(2017-02-20)
La neumonía adquirida en la comunidad (NAC) es un importante problema de salud pública con una elevada morbi-mortalidad. La incidencia anual oscila entre dos y ocho por cada 1000 habitantes. En Estados Unidos, junto con ...
Novel insights in the pathogenesis of primary biliary cholangitis and cholangiocarcinoma
(2017-06-23)
Este trabajo de tesis doctoral se centra en el estudio de dos enfermedades biliares: la colangitis biliar primaria (del inglés primary biliary cholangitis, PBC) y el colangiocarcinoma (CCA).Por un lado, ya que el miR-506 ...
The role of osteopontin in liver fibrosis
(2017-09-19)
Osteopontin (OPN) is a cytokine and matrix molecule that is upregulated in human and mouse models of chronic liver injury and directly promotes liver fibrogenesis by activating hepatic stellate cells (HSC) and liver ...
The effectiveness of a basic exercise intervention to improve strength and balance in women with osteoporosis
(Dove Medical Press, 2017-03-14)
Objective: To determine the effects of a simple exercise program on the balance and strength of postmenopausal women with osteoporosis.
Methods: This program was based on low intensity strength and balance exercises, ...
Sex differences in the aging pattern of renin–angiotensin system serum peptidases
(Biomed Central, 2017-02-03)
Background: Serum peptidases, such as angiotensin-converting enzyme (ACE), angiotensin-converting enzyme-2 (ACE2), neutral endopeptidase (NEP), aminopeptidase N (APN), and aminopeptidase A (APA), are important elements of ...
Plasma rich in growth factors to treat Knee Osteoarthritis
(2017-06-01)
En la tesis titulada Plasma Rich in Growth Factors to treat knee osteoarthritis se exponen 4 trabajosexperimentales basados en el uso del Plasma rico en factores de crecimiento. Los objetivos específicos delos trabajos ...
Expression of Adenosine A2B Receptor and Adenosine Deaminase in Rabbit Gastric Mucosa ECL Cells
(MDPI, 2017-04)
Adenosine is readily available to the glandular epithelium of the stomach. Formed continuously in intracellular and extracellular locations, it is notably produced from ATP released in enteric cotransmission. Adenosine ...
Adenosine: direct and indirect actions on gastric acid secretion
(Frontiers Media, 2017-09-22)
Composed by a molecule of adenine and a molecule of ribose, adenosine is a paradigm of recyclable nucleoside with a multiplicity of functions that occupies a privileged position in the metabolic and regulatory contexts. ...