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Phosphorylation of the carboxy-terminal domain of histone H1: effects on secondary structure and DNA condensation
(Oxford University Press, 2008-08)
Linker histone H1 plays an important role in chromatin folding. Phosphorylation by cyclin-dependent kinases is the main post-translational modification of histone H1. We studied the effects of phosphorylation on the secondary ...
Randomised, crossover clinical trial, in healthy volunteers, to compare the systemic availability of two topical intranasal budesonide formulations
(BioMed Central, 2008-06)
Background: Budesonide has a long history as intranasal drug, with many marketed products. Efforts should be made to demonstrate the therapeutic equivalence and safety comparability between them. Given that systemic ...
Ceramide-enriched membrane domains in red blood cells and the mechanism of sphingomyelinase-induced hot-cold haemolysis
(American Chemical Society, 2008-10-28)
Hot-cold hemolysis is the phenomenon whereby red blood cells, preincubated at 37 °C in
the presence of certain agents, undergo rapid hemolysis when transferred to 4 °C. The mechanism of this
phenomenon is not understood. ...