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Increased antiparkinson efficacy of the combined administration of VEGF- and GDNF-loaded nanospheres in a partial lesion model of Parkinson's disease

Herrán Martínez, Enara; Requejo Rodríguez, Catalina; Ruiz Ortega, José Ángel; Aristieta Arbelaiz, Asier; Igartua Olaechea, Manuela; Bengoetxea Odriozola, Harkaitz; Ugedo Urruela, Luisa; Pedraz Muñoz, José Luis; Lafuente Sánchez, José Vicente; Hernández Martín, Rosa María (Dove Medical Press, 2014)

Current research efforts are focused on the application of growth factors, such as glial cell line-derived neurotrophic factor (GDNF) and vascular endothelial growth factor (VEGF), as neuroregenerative approaches that will ...

The complex association between the antioxidant defense system and clinical status in early psychosis

García Fernández, Saínza; Alberich, Susana; Martínez Cengotitabengoa, Mónica; Arango, Celso; Castro-Fornieles, Josefina; Baeza, Inmaculada; Moreno, Carmen; Micó, Juan Antonio; Berrocoso, Esther; Graell, Montserrat; Otero, Soraya; Simal, Tatiana; González Pinto Arrillaga, Ana María (Public Library Science, 2018-04-26)

Oxidative stress is a pathophysiological mechanism potentially involved in psychiatric disorders. The objective of this study was to assess the relationship between total antioxidant status (TAS) and the functional status ...

Association Between Medication Adherence and Oxidative Stress in Patients With First-Episode Mania

García Fernández, Saínza; Alberich, Susana; MacDowell, Karina S.; Martínez Cengotitabengoa, Mónica; López Peña, María Purificación; Zorrilla Martínez, Iñaki; Leza, Juan Carlos; González Pinto Arrillaga, Ana María (Frontiers Media, 2019-03-26)

Poor adherence is a major problem in patients with manic episodes that impairs functionality and has unknown effects on oxidative stress. The objective of this study was to analyze the relationship between adherence to ...

Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action

Manchia, Mirko; Vieta, Eduard; Smeland, Olav B.; Altimus, Cara; Bechdolf, Andreas; Bellivier, Frank; Bergink, Veerle; Fagiolini, Andrea; Geddes, John; Hajek, Tomas; Henry, Chantal; Kupka, Ralph; Lagerberg, Trine V.; Licht, Rasmus W.; Martínez Cengotitabengoa, Mónica; Morken, Gunnar; Nielsen, René E.; González Pinto Arrillaga, Ana María; Reif, Andreas; Rietschel, Marcella; Ritter, Philipp; Schulze, Thomas G.; Scott, Jan; Severus, Emanuel; Yildiz, Aysegul; Kessing, Lars Vedel; Bauer, Michael; Goodwin, Guy M.; Andreassen, Ole A. (Elsevier, 2020-06-12)

[EN] Bipolar disorder (BD) is a major healthcare and socio-economic challenge. Despite its substan- tial burden on society, the research activity in BD is much smaller than its economic impact appears to demand. There is ...