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Osteopontin: a key regulator of liver lipid metabolism
(2016-04-25)
Osteopontin deficiency protects from obesity-related hepatosteatosis and liver fibrosis. Here we have investigated the role of osteopontin as a direct regulator of liver metabolism and whether osteopontin could be a ...
The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases
(Public Library Science, 2016-12-29)
Clear cell renal cell carcinoma (CCRCC) is a heterogeneous and complex disease that frequently develops distant metastases. Fibroblast activation protein (FAP) is a serine peptidase the expression of which in cancer-associated ...
Macrophage-dependent IL-1 beta production induces cardiac arrhythmias in diabetic mice
(Nature Publishing, 2016-11-24)
Diabetes mellitus (DM) encompasses a multitude of secondary disorders, including heart disease. One of the most frequent and potentially life threatening disorders of DM-induced heart disease is ventricular tachycardia ...
Role of SOX17 in the regulation of the biliary phenotype and in cholangiocarcinogenesis
(2016-03-07)
El colangiocarcinoma (CCA) es un grupo heterogéneo de cánceres que afecta a las células de los conductos biliares (i.e. colangiocitos) y que presenta elevada letalidad debido a su diagnóstico tardío y quimioresistencia. ...
Antitumoral actions of Vismia baccifera on human hepatocellular carcinoma HepG2
(2016-07-26)
Nowadays there is an increasing interest in finding bioactive compounds which can be used as chemopreventive agents against cancer. In this work, we have studied the antitumoral actions of aqueous extracts from leaves of ...
Expression and Localization of Opioid Receptors in Male Germ Cells and the Implication for Mouse Spermatogenesis
(Public Library Science, 2016-03-31)
The presence of endogenous opioid peptides in different testicular cell types has been extensively characterized and provides evidence for the participation of the opioid system in the regulation of testicular function. ...
Monetary Diet Cost, Diet Quality, and Parental Socioeconomic Status in Spanish Youth
(Public Library Science, 2016-09-13)
Background
Using a food-based analysis, healthy dietary patterns in adults are more expensive than less healthy ones; studies are needed in youth. Therefore, the objective of the present study was to determine relationships ...
Estudio del Sistema Renina Angiotensina como posible biomarcador para la mejora de los tratamientos de fecundación in vitro
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2016-03-22)
La infertilidad se ha convertido en un problema médico y social de gran importancia mundial, que afecta al 15% de las parejas en edad reproductiva. El desarrollo de las técnicas de reproducción asistida (TRA) supuso un ...