Now showing items 1-6 of 6
Influence of Two Vaccination Campaigns on Genetic Diversity of Invasive Neisseria meningitidis Isolates in Northern Spain (1997–2008)
(Public Library of Science, 2009-12-30)
Background: Neisseria meningitidis diversifies rapidly, due to its high recombination rates. The aim of this study was to analyze the possible impact of two vaccination campaigns (a once-off A/C polysaccharide vaccination ...
Weak effect of trans-10, cis-12-conjugated linoleic acid on body fat accumulation in adult hamsters
(Cambridge University Press, 2009-12-14)
It has been proposed that young animals and subjects are more responsive to conjugated linoleic acid (CLA) than the adults. Nevertheless, there is very little information concerning the effectiveness of CLA in adult animals. ...
A multi-gene analysis strategy identifies metabolic pathways targeted by trans-10, cis-12-conjugated linoleic acid in the liver of hamsters
(Cambridge University Press, 2009-08-28)
In mice, hepatic functions can be greatly affected by dietary trans-10, cis-12-conjugated linoleic acid (CLA). However, this phenomenon has been less documented in hamsters. In the present study, male hamsters were fed two ...
A Model of Ischemia-Induced Neuroblast Activation in the Adult Subventricular Zone
(Public Library of Science, 2009-04-23)
We have developed a rat brain organotypic culture model, in which tissue slices contain cortex-subventricular zone-striatum regions, to model neuroblast activity in response to in vitro ischemia. Neuroblast activation has ...
Differential Micro RNA Expression in PBMC from Multiple Sclerosis Patients
(Public Library of Science, 2009-07-20)
Differences in gene expression patterns have been documented not only in Multiple Sclerosis patients versus healthy controls but also in the relapse of the disease. Recently a new gene expression modulator has been identified: ...
The Number of Catalytic Elements Is Crucial for the Emergence of Metabolic Cores
(Public Library of Science, 2009-10-19)
Background: Different studies show evidence that several unicellular organisms display a cellular metabolic structure characterized by a set of enzymes which are always in an active state (metabolic core), while the rest ...