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Effectiveness of Mobile Applications to Quit Smoking: Systematic Review and Meta-Analysis
(E.U. European Publishing, 2021-04)
Introduction: Tobacco is the leading cause of preventable mortality. The use of mobile phones has grown exponentially, becoming a powerful tool to be used in health care.
Methods: In order to assess the effectiveness ...
Drug pollution and pharmacotherapy inpsychiatry: A“platypus”in the room
(Cambridge University Press, 2020)
Preoccupation about potential deleterious effects of pharmaceuticals in the environment is growing fast. Psychiatric pharmaceuticals have received particular attention because of their increasing use and their potential ...
AIE-featured tetraphenylethylene nanoarchitectures in biomedical application: Bioimaging, drug delivery and disease treatment
(Elsevier, 2021-11-15)
[EN]The development of aggregation-induced emission (AIE) has received extreme considerations from basic and clinical researches. To date, various luminogens with AIE property (AIEgens) have been broadly utilized in ...
Towards brain-tissue-like biomaterials
(Nature, 2020-07-09)
Many biomaterials have been developed which aim to match the elastic modulus of the brain for improved interfacing. However, other properties such as ultimate toughness, tensile strength, poroviscoelastic responses, energy ...
Cost-Effectiveness Analysis of Text Messaging to Support Health Advice for Smoking Cessation
(BioMed Central, 2021-02-15)
Background: Smoking in one of the most serious public health problems. It is well known that it constitutes a major risk factor for chronic diseases and the leading cause of preventable death worldwide. Due to high prevalence ...
Standardizing Salivary Lactoferrin Measurements to Obtain a Robust Diagnostic Biomarker for Alzheimer's Disease
(Wiley, 2021-05-02)
The search for new, robust, and reproducible biomarkers for Alzheimer's disease (AD) diagnosis is a challenge. We recently reported that salivary lactoferrin (Lf) could be presented as new biomarker candidate for AD, being ...
Cells, Materials, and Fabrication Processes for Cardiac Tissue Engineering
(Frontiers Media, 2020-08-11)
Cardiovascular disease is the number one killer worldwide, with myocardial infarction (MI) responsible for approximately 1 in 6 deaths. The lack of endogenous regenerative capacity, added to the deleterious remodelling ...
PDX-Derived Ewing’s Sarcoma Cells Retain High Viability and Disease Phenotype in Alginate Encapsulated Spheroid Cultures
(MDPI, 2021-02-19)
Ewing’s Sarcoma (ES) is the second most frequent malignant bone tumour in children and young adults and currently only untargeted chemotherapeutic approaches and surgery are available as treatment, although clinical trials ...
Decreased salivary lactoferrin levels are specific to Alzheimer's disease
(Elsevier, 2020-07)
Background: Evidences of infectious pathogens in Alzheimer's disease (AD) brains may suggest a deteriorated innate immune system in AD pathophysiology. We previously demonstrated reduced salivary lactoferrin (Lf) levels, ...
Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects
(Elsevier, 2022-02)
P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX) resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2, HIF-1alpha, miRNAs, and long noncoding ...