Search
Now showing items 921-930 of 1136
Replacement of Cysteine at Position 46 in the First Cysteine-Rich Repeat of the LDL Receptor
(Public Library Science, 2018-10-17)
Background and aims
Pathogenic mutations in the Low Density Lipoprotein Receptor gene (LDLR) cause Familial Hypercholesterolemia (FH), one of the most common genetic disorders with a prevalence as high as 1 in 200 in ...
Familial amyloidosis with polyneuropathy type 1 caused by transthyretin mutation Val50Met (Val30Met): 4 cases in a non-endemic area
(Elsevier, 2018-11)
Introduction: Transthyretin-related familial amyloid polyneuropathy (TTR-FAP) typically arises as an autonomic neuropathy primarily affecting small fibres and it occurs in adult patients in their second or third decades ...
New poly(ionic liquid)s based on poly(azomethine-pyridinium) salts and its use as heterogeneous catalysts for CO2 conversion
(Elsevier, 2018-07-21)
A fast and simple synthetic route towards a new family of poly(ionic liquids) based on aromatic crosslinked poly(azomethine-pyridinium) salts is described. These new polymers were prepared in one step from new diamine ...
Characterization of wnt signaling in tamoxifen resistant breast cancer stem/progenitor cells
(2018-12-20)
El tamoxifen, un antagonista de ER, es el tratamiento más común empleado para tratar a pacientes que expresan ER. Las células resistentes a tamoxifen están enriquecidas en células madre/progenitoras. La expresión de WNT1 ...
Modeling and Control of Oscillating Water Column Devices for Ocean Energy Conversion.
(2018-07-12)
The work elaborated in this Ph. D. thesis focused on the modeling and control of an OWC device installed in the NEREIDA wave power plant of Mutriku. The main contributions are the development of a proper MATLAB/Simulink ...
Contribution to the development of best available practices (BAPs) for a multi-biomarker approach in sentinel mussels based on a better understanding of the influence of confounding factors on biomarker values and responsiveness
(2018-09-21)
Comprender la influencia de la variabilidad natural en las respuestas biológicas a los contaminantes es de gran importancia para interpretar adecuadamente el estado de salud ambiental. Se ha seleccionado una serie de ...
Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer’s Disease
(Hindawi, 2018)
Synapse loss is an early manifestation of pathology in Alzheimer's disease (AD) and is currently the best correlate to cognitive decline. Microglial cells are involved in synapse pruning during development via the complement ...
Metabarcoding analysis of the eukaryotic planktonic communities of the Bilbao estuary
(2018-05-31)
El estudio de la biodiversidad de las comunidades de plancton de los estuarios resulta de gran interés debido a que son parte fundamental de las cadenas tróficas acuáticas y a su capacidad de responder relativamente rápido ...
Critical behavior of the ferromagnetic transition in GdSc(Si,Ge) intermetallic compounds
(Elsevier, 2018-07-26)
A complete study on the critical behavior of the paramagnetic to ferromagnetic transition in intermetallics GdScSi, GdScGe, GdSc(Si0.5Ge0.5) and Gd(Sc0.5Ti0.5)Ge has been carried out by means of magnetic as well as ...
Critical behavior study of magnetic transitions in Dy3Co single crystals
(Elservier, 2018-02-14)
An ac photopyroelectric calorimeter has been used to study the critical behaviour of the magnetic transitions in Dy3Co measuring thermal diffusivity, specific heat and thermal conductivity, at low temperature. There are ...